Table 3 Multivariate L1-Penalized Cox Regression Analysis

From: Trajectory of compensated metabolic dysfunction-associated steatohepatitis in a tertiary center with a large hispanic/latino population

All Cause Death

HR [95% CI]

Demographics: Age

1.24 [1.02–1.52]

Demographics: Driving Distance (km)

0.94 [0.79–1.12]

Lab: MELD Score

1.35 [1.15–1.58]

Lab: FIB–4 Score

1.21 [1.03–1.41]

Medication: Calcium Channel Blocker

1.47 [0.88–2.45]

Medication: Insulin

1.15 [0.60–2.20]

Medication: Sulfonylurea

1.51 [0.87–2.62]

Medication: Statin

1.22 [0.81–1.82]

Demographics: Native American/Alaskan/Hawaiian

1.29 [0.89–1.87]

Demographics: Baseline Year >= 2020

0.73 [0.48–1.12]

Lab: Abnormal Alkaline Phosphatase

2.19 [1.25–3.84]

Composite outcome

HR [95% CI]

Demographics: Age

1.12 [0.96–1.29]

Lab: MELD Score

1.42 [1.27–1.58]

Lab: FIB-4 Score

1.43 [1.26–1.61]

Comorbidity: Hyperlipidemia

0.78 [0.59–1.04]

Medication: ARB Inhibitor

0.70 [0.46–1.06]

Medication: Oral Diabetes Med

1.35 [1.00–1.83]

Medication: Aspirin/Clopidogrel

0.77 [0.51–1.15]

Demographics: Baseline Year >= 2020

0.74 [0.54–1.02]

Decompensation Symptoms

HR [95% CI]

Lab: MELD Score

1.34 [1.16–1.55]

Lab: FIB-4 Score

1.34 [1.17–1.52]

Demographics: Baseline Year >= 2020

0.75 [0.52–1.09]

  1. Bold values indicate statistical significance.