Fig. 5: Dyes with similar molecular weight, logP values, and charge to chemotherapeutics were used to enable rapid screening. | npj Biomedical Innovations

Fig. 5: Dyes with similar molecular weight, logP values, and charge to chemotherapeutics were used to enable rapid screening.

From: Systematic design of polybasic nanogels: influence of hydrophobic monomers on tunable physicochemical and biological properties

Fig. 5

A, B Single agent loading showed hydrophilic compound loading is minorly affected by variation in NG hydrophobicity, and trends with the volume swelling ratio (VSR) observed by dynamic light scattering. Hydrophobic loading is influenced by improved interactions between drug and hydrogel, and is able to overcome the decrease in VSR. C Competitive co-loading demonstrated similar trends. Data represent mean ± SEM (n = 3, *p < 0.05, **p < 0.01 from “None”).

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