Fig. 3: BRI-50054 Treatment Increases Free ω-3 PUFA Brain Levels.

A C57BL/6J mice (n = 3) treated with vehicle, 1.0 or 3.0 mg/kg/day IP BRI-50054 for 3 days. Brain levels of DHA (B), DPA (C) and EPA (D) were measured using a validated LC-MS/MS lipidomic assay. *p < 0.05, **p < 0.01, ***p < 0.001.