Fig. 2: Principal component analysis (PCA) of the ReDLat dataset and individuals from the 1000 Genome project (1000GP). | npj Dementia

Fig. 2: Principal component analysis (PCA) of the ReDLat dataset and individuals from the 1000 Genome project (1000GP).

From: Genetic contributions to Alzheimer’s disease and frontotemporal dementia in admixed Latin American populations

Fig. 2

Panels represent the main principal component (PC) comparisons. a, d, g: PC1 vs. PC2. b, e, h: PC1 vs. PC3. c, f, i PC2 vs. PC3. Different color schemes were used to differentiate sample origin. The 1000GP includes African (AFR), European (EUR), South Asian (SAS), East Asian (EAS) and Admixed American (AMR) individuals. ReDLat subcohorts include individuals from Argentina (ARG), Brazil (BRA), Chile (CHI), Colombia (COL), Mexico (MEX), and Peru (PER). Panels a, b, c show color-coded ReDLat cohort participants projected onto the 1000GP reference samples PCA (gray). ReDLat cohort genomes are colored according to their country of origin. d, e, f show the ReDLat cohort (magenta) plotted against the color-coded 1000GP subpopulations. Panels g, h, i show ReDLat cohort (magenta) overlaid on 1000GP cohort (gray).

Back to article page