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Sophie Beeren discusses the development of cyclodextrins, moving from laboratory curiosities to common ingredients in daily products, active pharmaceutical ingredients and building blocks for supramolecular chemistry.
Lidan Xing and Kang Xu explain how bis(sulfonyl)imide salts use fluorine, with its extreme stability and electronegativity, to balance solubility and stability for developing advanced battery chemistries.
Benjamin N. Bhawal examines the enigmatic history of ribose in chemistry, its multifaceted structure, and its role in the origin of life and the design of future therapeutics.
Thomas Schlatzer and Véronique Gouverneur discuss why the chemistry of calcium fluoride is challenging, and how imaginative thinking based on fundamental principles can create positive change for the fluorochemical industry.
Nina M. Allen, Guilherme A. Marczak Giorio and M. Carmen Galan discuss how select napthalene diimides, such as QN-302, have been developed into DNA G-quadruplex (G4) ligands with downstream anticancer activity.
Davide Zanetti, Cristian De Luca, and Davide Bonifazi discuss the resurgence of peri-xanthenoxanthene from a forgotten dye into a versatile organic semiconductor and sustainable photocatalyst, emphasizing its importance in photoredox catalysis.
Moses Dike and Shudipto Konika Dishari explore lignin’s historic journey alongside human civilization and showcase its game-changing potential to drive sustainability without compromising performance.
Zoe Hoffpauir and Audrey Lamb outline the history and prospects of riboflavin, also known as vitamin B2, a molecule found in food that is required for the formation of coenzymes involved in metabolic processes.
Elena De Vita and Rebecca Page reflect on the unique properties of phosphate, an essential building block with versatile functions in living systems. Modulating protein phosphorylation is an effective therapeutic strategy, with emerging approaches highlighting the continuous development in this area of drug discovery.
Paulina Krzyszowska and Ewa Pacholska-Dudziak recap the history of porphyrins, their biological relevance, and discuss examples of their use in modern applications.
Adam Noble discusses the diverse uses of eosin Y over its 150-year history, from its origin as a dye and pigment used by post-impressionist masters to its versatile reactivity as a catalyst in visible light photochemistry.
When one says the word alcohol to a non-chemist, it is typically in reference to ethanol, the first alcohol discovered. Chi Chen, Mahlet Garedew, and Stafford W. Sheehan toast ethanol’s past, present, and future.
Nitric oxide is at the heart of myriad environmental and biological processes. Pokhraj Ghosh and Timothy Warren explore the molecular interconnections and wide-ranging impacts of this molecule which is critical for the health of our planet.
In molecular biology, few molecules have had as profound an impact as Cas9. Madeleine King, Kayla Perry, Mitchell McAndrew and Audrone Lapinaite discuss how this multifunctional molecular tool of genetic engineering is revolutionizing multiple fields.
