Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
npj Dementia has APC waivers available that can be allocated upon acceptance on an ad-hoc basis. For additional information, contact the Journal Publisher, Alex Willis.
Ammonia, a metabolite produced in nearly all body tissues, including through branched-chain amino acid metabolism, can accumulate in the brain and induce functional changes, particularly in astrocytes. These changes suggest potential mechanisms that may link ammonia with the progression and worsening of Alzheimer’s disease.
