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In this issue of Nature Reviews Neurology, we launch a Collection that explores the multisystemic nature of neurological disease and highlights the importance of collaboration between neurology and other clinical specialties.
Nature Reviews Neurology is interviewing leading experts who are working at the interface between neurology and other clinical specialties. We spoke with uro-neurologist Jalesh N. Panicker about his work on urogenital dysfunction in people with neurological disease and initiatives to promote collaboration between the neurology and urology fields.
In this World View, María E. Garay-Serratos recounts how her mother developed chronic traumatic encephalopathy following decades of domestic violence. She describes her quest to obtain a conclusive diagnosis for her mother and calls for increased awareness of and research into the link between domestic violence and chronic traumatic encephalopathy.
Nature Reviews Neurology is interviewing leading experts who are working at the interface between neurology and other clinical specialties. We spoke with stroke neurologist Luciano Sposato about his work on brain–heart interactions and initiatives to promote collaboration between the neurology and cardiology fields.
Macrophages in the gastrointestinal system have a key role in the development and propagation of α-synuclein pathology in body-first Parkinson disease, according to new research.
A new study has identified a previously unrecognized subset of brain fibroblasts that form a barrier at the base of the choroid plexus. In the healthy brain, this barrier restricts the movement of small molecules and immune cells, but it breaks down under inflammatory conditions.
Beth Grimsey lives with relapsing–remitting multiple sclerosis (MS) and is the Research Programme Manager at the MS Society in the UK. In this World View, she reflects on the uncertainty of MS, the ripple effects in families and the need for healthcare providers to communicate the knowns and unknowns.
Parkinson disease (PD) is the fastest growing neurodegenerative condition worldwide, and proposed explanations for this growth include ageing, increased environmental exposures and better recognition. Using an adaptation of the classical epidemiological bathtub as a metaphor, we consider the potential contributions of epidemiological dynamics to the growth in PD and their implications for PD research.
The natural migration pathway of CNS immune cells can be harnessed to deliver therapy to brain lesions in acute stroke, bypassing the blood–brain barrier (BBB), according to a new study published in Cell.
Loss of TDP43 from the nucleus in amyotrophic lateral sclerosis and frontemporal dementia leads to changes in polyadenylation that alter mRNA processing, according to new research.
Recent research indicates that the brain-first and body-first subtypes of Parkinson disease can be distinguished by patterns of cutaneous α-synuclein deposition.
Nature Reviews Neurology is interviewing individuals who are driving efforts to address disparities in neurology through a broad spectrum of diversity, equity and inclusion initiatives. We spoke with Victor Rivera from Baylor College of Medicine about his work to address disparities in multiple sclerosis care in Latin American and other populations.
Developmental trajectories and genetic architectures differ between inidividuals with autism who are diagnosed early or later in life, new research has shown.
