Duygan et al. develop a supervised machine learning algorithm, CellCognize, to quantify cell type diversity from multidimensional flow cytometry data. Their model achieves 80% prediction accuracy, detects shifts in microbial communities of unknown composition and quantifies population growth and biomass productivity. Their work will be useful to study microbiota in human health or engineered systems.
- Birge D. Özel Duygan
- Noushin Hadadi
- Jan R. van der Meer