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Showing 1–50 of 956 results

Advanced filters: Author: A E Fink Clear advanced filters

Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C

KRAS is an oncogene that switches between a GDP-bound inactive state and a GTP-bound active state. Recently developed KRAS G12C inhibitors are specific to the GDP-bound inactive state. Here, the authors develop a class of covalent KRAS G12C inhibitors capable of targeting both states for the treatment of KRAS-driven cancer.

Matthew L. Condakes
Zhuo Zhang
Michelle L. Stewart
ResearchOpen Access31 Jan 2026
Nature Communications

P: 1-15
Crystal structure of elastase–substrate complex at −55 °C

T. Alber
G. A. Petsko
D. Tsernoglou
Research23 Sept 1976
Nature

Volume: 263, P: 297-300
Polar discontinuities, emergent conductivity, and critical twist-angle-dependent behaviour at wafer-bonded ferroelectric interfaces

Wafer bonding has allowed the synthesis of twisted interfaces which support polar discontinuities in ferroelectric lithium niobate. Two-dimensional sheet conductivity arises but is suppressed when twist angles lead to interfacial lattice aperiodicity.

Andrew Rogers
Kristina Holsgrove
J. Marty Gregg
ResearchOpen Access23 Jan 2026
Nature Communications

P: 1-9
Gene conversion between duplicated genetic elements in yeast

Jennifer A. Jackson
Gerald R. Fink
Research23 Jul 1981
Nature

Volume: 292, P: 306-311
Molten globular characteristics of the native state of apomyoglobin

Laura Lin
Rachel J. Pinker
Neville R. Kallenbach
Research01 Jul 1994
Nature Structural Biology

Volume: 1, P: 447-452
Selective Extraction of a Protein Fraction from Wool Keratin

R. A. DEDEURWAERDER
M. G. DOBB
B. J. SWEETMAN
Research01 Jul 1964
Nature

Volume: 203, P: 48-49
Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response

Alicia M. Fry
Louis A. Matis
Research27 Oct 1988
Nature

Volume: 335, P: 830-832
Will blockbuster obesity drugs revolutionize addiction treatment?

Scientists are testing whether GLP-1 drugs can help to cut cravings for cigarettes, alcohol and opioids — as well as food.

Elie Dolgin
News02 Dec 2025
Nature

Volume: 648, P: 20-22
Fractionation of Ribonucleic Acids

R. BARBER
A. S. JONES
Research01 Jul 1964
Nature

Volume: 203, P: 45-48
Gonadotropin-releasing hormone surge in pro-oestrous rats

D. K. SARKAR
SHARON A. CHIAPPA
NANCY M. SHERWOOD
Research02 Dec 1976
Nature

Volume: 264, P: 461-463
The automation of optical transient discovery and classification in Rubin-era time-domain astronomy

The automated detection of transient phenomena in the sky has developed rapidly in recent years, driven by robotic telescopes such as the Zwicky Transient Facility and the Asteroid Terrestrial-impact Last Alert System. Here the authors summarize the state of the art and look ahead to more discoveries during the Legacy Survey of Space and Time era.

Nabeel Rehemtulla
Michael W. Coughlin
Theophile Jegou du Laz
Reviews08 Dec 2025
Nature Astronomy

Volume: 9, P: 1764-1769
Curare can open and block ionic channels associated with cholinergic receptors

A. Trautmann
Research15 Jul 1982
Nature

Volume: 298, P: 272-275
Osmotic Pressure Effect of the Red Blood Cells-Possible Physiological Significance

A. TYBJAERG HANSEN
Research06 May 1961
Nature

Volume: 190, P: 504-508
Multiscale red blood cell hitchhiking for targeted deep tissue gene delivery in lungs

Gene therapies often fail to reach tissues beyond the liver after intravenous delivery. Here, authors present MARVEL, a strategy that combines red blood cell hitchhiking with VEGF-induced vascular permeabilization to enhance lung targeting and deep tissue gene expression.

Kyung Soo Park
Vineeth Chandran Suja
Bijay Singh
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-11
Oxytocin Antibody and Lactation and Parturition in Rats

P. KUMARESAN
A. KAGAN
S. M. GLICK
Research16 Apr 1971
Nature

Volume: 230, P: 468-469
Experimental test of photonic entanglement in accelerated reference frames

The unification of the theory of relativity and quantum mechanics is a long-standing challenge in physics. Here the authors investigate the effects of a wide range of accelerations on an entangled photon pair, providing an upper bound for the effects of non-inertial frames on quantum systems.

Matthias Fink
Ana Rodriguez-Aramendia
Rupert Ursin
ResearchOpen Access10 May 2017
Nature Communications

Volume: 8, P: 1-6
Unidentified features in the spectrum of Triton

G. H. Rieke
L. A. Lebofsky
E. F. Montgomery
Research05 Nov 1981
Nature

Volume: 294, P: 59-60
To every man his own language: Are we all Darwin’s children?

Shantanu Ghosh
ResearchOpen Access30 Nov 2007
Nature Precedings

P: 1
Isolation of a gene from Drosophila by complementation in yeast

Steven Henikoff
Kelly Tatchell
Kim A. Nasmyth
Research01 Jan 1981
Nature

Volume: 289, P: 33-37
Mucoproteins of Bronchial Mucus

M. Z. ATASSI
S. A. BARKER
K. S. MULLARD
Research30 Dec 1961
Nature

Volume: 192, P: 1269-1270
Sulphur flows at Lastarria volcano in the North Chilean Andes

J. A. Naranjo
Research28 Feb 1985
Nature

Volume: 313, P: 778-780
Output control of dissipative nonlinear multimode amplifiers using spacetime symmetry mapping

In many optical systems with time-reversal symmetry, it is possible to control the output waves by shaping the input fields. Now a scheme is presented that works for multimode fibres that lack time-reversal symmetry due to thermal effects.

Chun-Wei Chen
Kabish Wisal
Hui Cao
Research01 Apr 2025
Nature Physics

Volume: 21, P: 839-845
Hæmoglobin in Fungi: Hæmoglobin in Moulds: Neurospora crassa and Penicillium notatum

D. KEILIN
A. TISSIÈRES
Research29 Aug 1953
Nature

Volume: 172, P: 393-394
Effect of Hydrogen Ion Concentration on the Dissociation of Calcium Albuminate

N. A. PETERSON
J. M. CRISMON
G. A. FEIGEN
Research03 Feb 1962
Nature

Volume: 193, P: 439-441
The impact on marriages of adult-onset paraplegia

Kathleen Shea Abrams
Research01 Aug 1981
Spinal Cord

Volume: 19, P: 253-259
Effect of Oxygen in Mammalian Cells Sensitized to Radiation by Incorporation of 5-Bromodeoxyuridine into the DNA

R. M. HUMPHREY
W. C. DEWEY
A. CORK
Research20 Apr 1963
Nature

Volume: 198, P: 268-269
The Evolution of Overdominance: Natural Selection and Heterozygote Advantage

P. A. PARSONS
W. F. BODMER
Research01 Apr 1961
Nature

Volume: 190, P: 7-12
Homing receptor-bearing thymocytes, an immunocompetent cortical subpopulation

Pamela J. Fink
W. Michael Gallatin
Irving L. Weissman
Research17 Jan 1985
Nature

Volume: 313, P: 233-235
Covariation MS uncovers a protein that controls cysteine catabolism

A mass spectrometry-based approach globally identifies protein regulators of metabolism and reveals the role of LRRC58 in controlling cysteine catabolism.

Haopeng Xiao
Martha Ordonez
Edward T. Chouchani
ResearchOpen Access17 Sept 2025
Nature

Volume: 647, P: 268-276
The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism

Kinesin-14 (Ncd in Drosophila, and Klp2 in fission yeast) is a microtubule-based motor important for spindle assembly. Ncd and Klp2 mediate both sliding of anti-parallel microtubules and crosslinking of parallel ones.

Marcus Braun
Douglas R. Drummond
Andrew D. McAinsh
Research10 May 2009
Nature Cell Biology

Volume: 11, P: 724-730
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals

Charles Scafe
David Chao
Richard A. Young
Research04 Oct 1990
Nature

Volume: 347, P: 491-494
Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

James A.R. Nicoll
Gareth W. Roberts
David I. Graham
Research01 Feb 1995
Nature Medicine

Volume: 1, P: 135-137
Recombination occurs during telomere formation in yeast

Ann F. Pluta
Virginia A. Zakian
Research02 Feb 1989
Nature

Volume: 337, P: 429-433
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase

Marie-Anne Félix
Jean-Claude Labbé
Eric Karsenti
Research26 Jul 1990
Nature

Volume: 346, P: 379-382
Evolution of homeothermy in mammals

A. W. Crompton
C. Richard Taylor
James A. Jagger
Research01 Mar 1978
Nature

Volume: 272, P: 333-336
In silico study of the sensing properties of C18, B9N9, and Al9N9 nanorings for diabetes monitoring via indole detection in exhaled breath

Abdulwahab Alamri
Ahmed Alafnan
ResearchOpen Access24 Dec 2025
Scientific Reports

Volume: 16, P: 1-16
Brain immunoreactive gonadotropin-releasing hormone in Huntington's chorea and in non-choreic subjects

E. D. BIRD
SHARON A. CHIAPPA
G. FINK
Research08 Apr 1976
Nature

Volume: 260, P: 536-538
Mercury-206: a New Natural Radionuclide

M. NURMIA
P. KAURANEN
A. LYYJYNEN
Research29 Apr 1961
Nature

Volume: 190, P: 427-428
Separation of RNA-dependent DNA Polymerase Activity from the Murine Leukaemia Virion

BRENDA I. GERWIN
GEORGE J. TODARO
STUART A. AARONSON
Research31 Oct 1970
Nature

Volume: 228, P: 435-438
Atomic scale real-space mapping of holes in YBa₂Cu₃O_6+δ

The properties of many high-temperature superconductors are governed by holes rather than electrons. Gauquelin et al. use atomic resolution electron energy loss spectroscopy to study the effect of oxygen doping on the valence of Cu ions and local electronic structure around the oxygen atoms in YBa₂Cu₃O_6+δ.

N. Gauquelin
D. G. Hawthorn
G. A. Botton
Research15 Jul 2014
Nature Communications

Volume: 5, P: 1-7
Search for a Human Breast Cancer Virus

DAN H. MOORE
JESSE CHARNEY
A. B. VAIDYA
Research26 Feb 1971
Nature

Volume: 229, P: 611-615
Large-scale cryovolcanic resurfacing on Pluto

Giant icy volcanos (cryovolcanos) on Pluto are unique in the imaged solar system and provide evidence for unexpected, active geology late in Pluto’s history.

Kelsi N. Singer
Oliver L. White
Kimberly Ennico-Smith
ResearchOpen Access29 Mar 2022
Nature Communications

Volume: 13, P: 1-9
Superconductivity from a melted insulator in Josephson junction arrays

Predictions of a quantum superconductor–insulator transition in Josephson junction arrays are not always borne out by experiments. Unexpectedly large thermal effects may explain why.

S. Mukhopadhyay
J. Senior
A. P. Higginbotham
ResearchOpen Access10 Aug 2023
Nature Physics

Volume: 19, P: 1630-1635
Embryopathic Effects of 7,12-Dimethylbenz(a)anthracene and its Hydroxymethyl Derivatives in the Sprague–Dawley Rat

A. R. CURRIE
C. C. BIRD
P. SIMS
Research06 Jun 1970
Nature

Volume: 226, P: 911-914
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

Stephen M. Hedrick
David I. Cohen
Mark M. Davis
Research08 Mar 1984
Nature

Volume: 308, P: 149-153
A 'molten-globule' membrane-insertion intermediate of the pore-forming domain of colicin A

F. G. van der Goot
J. M. González-Mañas
F. Pattus
Research05 Dec 1991
Nature

Volume: 354, P: 408-410
Bacterial conjugative plasmids mobilize DNA transfer between bacteria and yeast

Jack A. Heinemann
George F. Sprague Jr
Research20 Jul 1989
Nature

Volume: 340, P: 205-209
Preliminary Characterization of Two Species of dsRNA in Yeast and their Relationship to the “Killer” Character

E. A. BEVAN
A. J. HERRING
DIANE J. MITCHELL
Research14 Sept 1973
Nature

Volume: 245, P: 81-86
Haemoglobin switching in human embryos: asynchrony of ζ → α and ε → γ-globin switches in primitive and definitive erythropoietic lineage

C. Peschle
F. Mavilio
G. Mastroberardino
Research17 Jan 1985
Nature

Volume: 313, P: 235-238
Construction of a mouse yeast artificial chromosome library in a recombination–deficient strain of yeast

F. L. Chartier
J. T. Keer
S. D. M. Brown
Research01 May 1992
Nature Genetics

Volume: 1, P: 132-136

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