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Showing 1–50 of 59 results

Advanced filters: Author: A Levitzki Clear advanced filters

Re-evaluation of the number of specific β-adrenergic receptors on muscle cells (reply)

D. ATLAS
E. HANSKI
A. LEVITZKI
Research04 Jan 1979
Nature

Volume: 277, P: 59-60
Inhibition of pp60^c-Src reduces Bcl-X_L expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

Rotem Karni
Richard Jove
Alexander Levitzki
Research18 Aug 1999
Oncogene

Volume: 18, P: 4654-4662
Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s)

E Suarez Pestana
U Greiser
F-D Böhmer
Research01 Jan 1997
British Journal of Cancer

Volume: 75, P: 213-220
Concanavalin A blocks desensitisation of glutamate receptors on insect muscle fibres

D. A. MATHERS
P. N. R. USHERWOOD
Research05 Feb 1976
Nature

Volume: 259, P: 409-411
Fundamental difference between the molecular interactions of agonists and antagonists with the β-adrenergic receptor

Gregory A. Weiland
Kenneth P. Minneman
Perry B. Molinoff
Research13 Sept 1979
Nature

Volume: 281, P: 114-117
Oxidase-like Activity of the Copper (II) Poly-L-histidine Complex

A. LEVITZKI
I. PECHT
M. ANBAR
Research01 Sept 1965
Nature

Volume: 207, P: 1386-1387
New evidence on the location of the saccharide-binding site of concanavalin A

J. W. BECKER
G. N. REEKE JR
G. M. EDELMAN
Research05 Feb 1976
Nature

Volume: 259, P: 406-409
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

N. Li
A. Batzer
J. Schlessinger
Research06 May 1993
Nature

Volume: 363, P: 85-88
Transglutaminase is essential in receptor-mediated endocytosis of α₂-macroglobulin and polypeptide hormones

Peter J. A. Davies
Dana R. Davies
Ira H. Pastan
Research10 Jan 1980
Nature

Volume: 283, P: 162-167
Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

P. De Meyts
E. Van Obberghen
D. Brandenburg
Research15 Jun 1978
Nature

Volume: 273, P: 504-509
Colchicine potentiates β-adrenoreceptor-stimulated cyclic AMP in lymphoma cells by an action distal to the receptor

PAUL A. INSEL
MICHAEL S. KENNEDY
Research01 Jun 1978
Nature

Volume: 273, P: 471-473
The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

Samantha E. Greasley
Harren Jhoti
Ben Bax
Research01 Sept 1995
Nature Structural Biology

Volume: 2, P: 797-806
Substantia nigra of the rat contains a dopamine sensitive adenylate cyclase

O. T. PHILLIPSON
A. S. HORN
Research03 Jun 1976
Nature

Volume: 261, P: 418-420
Effect of Concanavalin A on Lymphocyte-mediated Cytotoxicity

L. STAVY
A. J. TREVES
M. FELDMAN
Research02 Jul 1971
Nature

Volume: 232, P: 56-58
Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway

Arthur M. Buchberg
Linda S. Cleveland
Neal G. Copeland
Research20 Sept 1990
Nature

Volume: 347, P: 291-294
A bright nearby supernova

Roger A. Chevalier
News & Views05 Feb 1981
Nature

Volume: 289, P: 441-442
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Roy Garcia
Tammy L Bowman
Richard Jove
Research03 May 2001
Oncogene

Volume: 20, P: 2499-2513
Killing time for cancer cells

Shoshana Klein
Frank McCormick
Alexander Levitzki
Reviews20 Jun 2005
Nature Reviews Cancer

Volume: 5, P: 573-580
Hydrogen peroxide mediates doxorubicin-induced transglutaminase 2 expression in PC-14 human lung cancer cell line

Jeong A Han
Sang Chul Park
ResearchOpen Access01 Jun 1999
Experimental & Molecular Medicine

Volume: 31, P: 83-88
A functional screen in yeast for regulators and antagonizers of heterologous protein tyrosine kinases

Giulio Superti-Furga
Katarina Jönsson
Sara A. Courtneidge
Research01 May 1996
Nature Biotechnology

Volume: 14, P: 600-605
Modulation of adipocyte G-protein expression in cancer cachexia by a lipid-mobilizing factor (LMF)

B Islam-Ali
S Khan
M J Tisdale
ResearchOpen Access28 Aug 2001
British Journal of Cancer

Volume: 85, P: 758-763
Cisplatin and taxol activate different signal pathways regulating cellular injury-induced expression of GADD153

DP Gately
A Sharma
SB Howell
Research01 Jan 1996
British Journal of Cancer

Volume: 73, P: 18-23
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

Lanxi Song
James Turkson
Eric B Haura
Research02 Jul 2003
Oncogene

Volume: 22, P: 4150-4165
EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer

Rina Hui
Douglas H Campbell
Robert L Sutherland
Research25 Sept 1997
Oncogene

Volume: 15, P: 1617-1623
The discovery of receptor tyrosine kinases: targets for cancer therapy

Andreas Gschwind
Oliver M. Fischer
Axel Ullrich
Reviews01 May 2004
Nature Reviews Cancer

Volume: 4, P: 361-370
Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay

Y Zlotnik
M Patya
A Novogrodsky
ResearchOpen Access18 Jan 2005
British Journal of Cancer

Volume: 92, P: 294-297
A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity

S Goldoni
R A Iozzo
R V Iozzo
Research17 Jul 2006
Oncogene

Volume: 26, P: 368-381
The ERBB network: at last, cancer therapy meets systems biology

This Timeline article focuses on the ERBB network of receptor tyrosine kinases, which exemplifies how a constant dialogue between basic and clinical cancer research can lead to the development of both novel drugs and strategies to overcome acquired resistance.

Yosef Yarden
Gur Pines
Reviews12 Jul 2012
Nature Reviews Cancer

Volume: 12, P: 553-563
ERBB receptors and cancer: the complexity of targeted inhibitors

Nancy E. Hynes
Heidi A. Lane
Reviews01 May 2005
Nature Reviews Cancer

Volume: 5, P: 341-354
Comparative genomic hybridization and chromosomal instability in solid tumours

P H Rooney
G I Murray
H L McLeod
ResearchOpen Access23 Apr 1999
British Journal of Cancer

Volume: 80, P: 862-873
Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions

L O Murphy
M W Cluck
T E Adrian
ResearchOpen Access03 Apr 2001
British Journal of Cancer

Volume: 84, P: 926-935
Development of inhibitors for protein tyrosine kinases

Fahad A Al-Obeidi
Kit S Lam
Research20 Nov 2000
Oncogene

Volume: 19, P: 5690-5701
Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232

C-C Diaconu
M Szathmári
A Venetianer
ResearchOpen Access28 May 1999
British Journal of Cancer

Volume: 80, P: 1197-1203
Cisplatin induces PKB/Akt activation and p38^MAPK phosphorylation of the EGF receptor

S E Winograd-Katz
A Levitzki
Research19 Jun 2006
Oncogene

Volume: 25, P: 7381-7390
The tumor-specific de2–7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR

Rodney B Luwor
Hong-Jian Zhu
Terrance G Johns
Research28 Jun 2004
Oncogene

Volume: 23, P: 6095-6104
c-Src Activation by the E5 oncoprotein enables transformation independently of PDGF receptor activation

Frank A Suprynowicz
Astrid Baege
Richard Schlegel
Research08 Mar 2002
Oncogene

Volume: 21, P: 1695-1706
Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor α

E Schausberger
K Hufnagl
B Grasl-Kraupp
ResearchOpen Access09 Nov 2004
British Journal of Cancer

Volume: 91, P: 1955-1963
Collective behaviours: from biochemical kinetics to electronic circuits

Elena Agliari
Adriano Barra
Guido Uguzzoni
ResearchOpen Access10 Dec 2013
Scientific Reports

Volume: 3, P: 1-15
STAT proteins: novel molecular targets for cancer drug discovery

James Turkson
Richard Jove
Reviews27 Dec 2000
Oncogene

Volume: 19, P: 6613-6626
Facilitated engraftment of human hematopoietic cells in severe combined immunodeficient mice following a single injection of Cl₂MDP liposomes

W Terpstra
PJM Leenen
B Löwenberg
Research01 Jul 1997
Leukemia

Volume: 11, P: 1049-1054
The in vitro activity of the tyrosine kinase inhibitor STI571 in BCR–ABL positive chronic myeloid leukaemia cells: synergistic interactions with anti-leukaemic agents

W M Liu
L A Stimson
S P Joel
ResearchOpen Access07 May 2002
British Journal of Cancer

Volume: 86, P: 1472-1478
Differential effect of polyunsaturated fatty acids on cell proliferation during human epithelial in vitro carcinogenesis: involvement of epidermal growth factor receptor tyrosine kinase

S Mollerup
A Haugen
Research01 Aug 1996
British Journal of Cancer

Volume: 74, P: 613-618
Targeting melanoma with NT157 by blocking Stat3 and IGF1R signaling

E Flashner-Abramson
S Klein
A Levitzki
Research29 Jun 2015
Oncogene

Volume: 35, P: 2675-2680
Role of Src expression and activation in human cancer

Rosalyn B Irby
Timothy J Yeatman
Research20 Nov 2000
Oncogene

Volume: 19, P: 5636-5642
Targeting the EGF receptor in ovarian cancer with the tyrosine kinase inhibitor ZD 1839 (‘Iressa’)

J M Sewell
K G Macleod
S P Langdon
ResearchOpen Access11 Feb 2002
British Journal of Cancer

Volume: 86, P: 456-462
Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process

Chunrong Yu
Mohamed Rahmani
Steven Grant
Research01 Dec 2003
Oncogene

Volume: 23, P: 1364-1376
RNA interference against a glioma-derived allele of EGFR induces blockade at G₂M

Qi-Wen Fan
William A Weiss
Research06 Dec 2004
Oncogene

Volume: 24, P: 829-837
Herbimycin A accelerates the induction of apoptosis following etoposide treatment or γ-irradiation of bcr/abl-positive leukaemia cells

Fiona A Riordan
Christopher A Bravery
R Gitendra Wickremasinghe
Research01 Apr 1998
Oncogene

Volume: 16, P: 1533-1542
Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs

Richard J Pietras
Mark D Pegram
Dennis J Slamon
Research29 Oct 1998
Oncogene

Volume: 17, P: 2235-2249
GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF

H Rozemuller
W Terpstra
ACM Martens
Research08 Dec 1998
Leukemia

Volume: 12, P: 1962-1970