Nature Search

Environmental impacts and monetary costs of healthy diets worldwide

Identifying low-cost options for a healthy diet is an essential step towards allowing all people to meet their nutritional needs. This study measures the frontiers of the lowest available cost and greenhouse gas emissions for a healthy diet in 171 countries, as well as healthy diets reflecting consumption patterns in each country.

Yan Bai
Elena M. Martinez
William A. Masters
Research09 Dec 2025
Nature Food

Volume: 6, P: 1176-1185
Effect of weight loss and regional fat distribution on plasma leptin concentration in obese women

P Rissanen
S Mäkimattila
A Rissanen
Research26 Jun 1999
International Journal of Obesity

Volume: 23, P: 645-649
Idiosyncratic Mòjiāng virus attachment glycoprotein directs a host-cell entry pathway distinct from genetically related henipaviruses

The attachment glycoprotein (HNV-G) of henipaviruses interacts with host receptors at the cell surface and is a major determinant of species tropism. Here the authors provide structural and functional evidence that the emergent henipavirus, Mòjiang virus, uses an entry mechanism that is independent of known paramyoxviral cellular receptors.

Ilona Rissanen
Asim A. Ahmed
Thomas A. Bowden
ResearchOpen Access12 Jul 2017
Nature Communications

Volume: 8, P: 1-11
Nutritional deficiencies in German middle-class male alcohol consumers: relation to dietary intake and severity of liver disease

I Bergheim
A Parlesak
C Bode
Research10 Mar 2003
European Journal of Clinical Nutrition

Volume: 57, P: 431-438
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Here, the authors perform large trans-ancestry fine-mapping analyses identifying large numbers of association signals and putative target genes for colorectal cancer risk, advancing our understanding of the genetic and biological basis of this cancer.

Zhishan Chen
Xingyi Guo
Wei Zheng
ResearchOpen Access26 Apr 2024
Nature Communications

Volume: 15, P: 1-17
Environmental factors in the development of obesity in identical twins

P Hakala
A Rissanen
T Rönnemaa
Research10 Aug 1999
International Journal of Obesity

Volume: 23, P: 746-753
Input–output maps are strongly biased towards simple outputs

Algorithmic information theory measures the complexity of strings. Here the authors provide a practical bound on the probability that a randomly generated computer program produces a given output of a given complexity and apply this upper bound to RNA folding and financial trading algorithms.

Kamaludin Dingle
Chico Q. Camargo
Ard A. Louis
ResearchOpen Access22 Feb 2018
Nature Communications

Volume: 9, P: 1-7
Sick leave and disability pension before and after treatment for obesity: A report from the Swedish Obese Subjects (SOS) study

K Narbro
G Ågren
L Sjöström
Research26 Jun 1999
International Journal of Obesity

Volume: 23, P: 619-624
Automatic differentiation of voluntary and tremulous motion using ensemble empirical mode decomposition and convolutional Bi-directional LSTM

Jie Qi Ling
A. S. M. Bakibillah
Chee Pin Tan
ResearchOpen Access08 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris

CR Hankey
MEJ Lean
M Woodward
Research24 Sept 2002
European Journal of Clinical Nutrition

Volume: 56, P: 1039-1045
Stroke genetics informs drug discovery and risk prediction across ancestries

A cross-ancestry meta-analysis of genome-wide association studies identifies association signals for stroke and its subtypes at 89 (61 new) independent loci, reveals putative causal genes, highlighting F11, KLKB1, PROC, GP1BA, LAMC2 and VCAM1 as potential drug targets, and provides cross-ancestry integrative risk prediction.

Aniket Mishra
Rainer Malik
Stephanie Debette
ResearchOpen Access30 Sept 2022
Nature

Volume: 611, P: 115-123
New Insights into Mechanical, Metabolic and Muscle Oxygenation Signals During and After High-Intensity Tethered Running

F. B. Manchado-Gobatto
A. B. Marostegan
C. A Gobatto
ResearchOpen Access14 Apr 2020
Scientific Reports

Volume: 10, P: 1-14
Anthropogenic organic aerosol in Europe produced mainly through second-generation oxidation

Second-generation oxidation boosts the production of anthropogenic organic aerosol, according to an analysis of urban haze in an experimental chamber.

Mao Xiao
Mingyi Wang
Imad El Haddad
ResearchOpen Access10 Mar 2025
Nature Geoscience

Volume: 18, P: 239-245
A chemically and electrochemically switchable molecular shuttle

Richard A Bissell
Emilio Córdova
J. Fraser Stoddart
Research12 May 1994
Nature

Volume: 369, P: 133-137
Trapping, detection and reaction of very large single molecular ions by mass spectrometry

R. D. Smith
X. Cheng
G. A. Anderson
Research12 May 1994
Nature

Volume: 369, P: 137-139
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

A multi-ancestry genome-wide association study meta-analysis, combined with transcriptome- and methylome-wide association analyses, identifies risk loci associated with colorectal cancer. Credible effector genes and their target tissues are also highlighted, showing that over a third probably act outside the colonic mucosa.

Ceres Fernandez-Rozadilla
Maria Timofeeva
Ulrike Peters
Research20 Dec 2022
Nature Genetics

Volume: 55, P: 89-99
Effect of orlistat treatment on body composition and resting energy expenditure during a two-year weight-reduction programme in obese Finns

L Karhunen
A Franssila-Kallunki
M Uusitupa
Research04 Dec 2000
International Journal of Obesity

Volume: 24, P: 1567-1572
Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants

Here the authors describe a small antibody-like protein that can prevent infection by diverse SARS-CoV-2 variants in cell culture and in mice that were intranasally treated with this inhibitor before or shortly after being exposed to the virus.

Anna R. Mäkelä
Hasan Uğurlu
Kalle Saksela
ResearchOpen Access24 Mar 2023
Nature Communications

Volume: 14, P: 1-12
Comparison of toremifene and tamoxifen in post-menopausal patients with advanced breast cancer: a randomized double-blind, the 'nordic' phase III study

S Pyrhönen
R Valavaara
A Hajba
Research01 Jul 1997
British Journal of Cancer

Volume: 76, P: 270-277
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Ruth Loos and colleagues report results of a large genome-wide association study for body mass index. They identify 18 new loci associated with this trait, some of which map near key hypothalamic regulators of energy balance.

Elizabeth K Speliotes
Cristen J Willer
Ruth J F Loos
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 937-948
Determinants of resting energy expenditure in obese non-diabetic caucasian women

L Karhunen
A Franssila-Kallunki
M Uusitupa
Research01 Mar 1997
International Journal of Obesity

Volume: 21, P: 197-202
Predictors of major weight gain in adult Finns: Stress, life satisfaction and personality traits

M Korkeila
J Kaprio
TIA Sörensen
Research07 Oct 1998
International Journal of Obesity

Volume: 22, P: 949-957
The 10-year COPD Programme in Finland: effects on quality of diagnosis, smoking, prevalence, hospital admissions and mortality

Vuokko L Kinnula
Tuula Vasankari
Anne Pietinalho
Research23 Mar 2011
Primary Care Respiratory Journal

Volume: 20, P: 178-183
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Cecilia Lindgren and colleagues report results of a large-scale genome-wide association study for waist-to-hip ratio, a measure of body fat distribution. They identify 13 new loci associated with this trait, several of which show stronger effects in women than in men.

Iris M Heid
Anne U Jackson
Cecilia M Lindgren
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 949-960
Cardiac expression profiles of the naked DNA vectors encoding vascular endothelial growth factor and basic fibroblast growth factor

Jung-Sun Lee
Jonghoe Byun
Duk-Kyung Kim
ResearchOpen Access01 Oct 2005
Experimental & Molecular Medicine

Volume: 37, P: 447-456
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source

Iodic acid (HIO₃) forms aerosols very efficiently, but its gas-phase formation mechanism is not well understood. Atmospheric simulation chamber experiments, quantum chemical calculations and kinetic modelling have now revealed that HIO₃ forms as an early iodine oxidation product from hypoiodite. The mechanism explains field measurements and suggests a catalytic role for iodine in particle formation.

Henning Finkenzeller
Siddharth Iyer
Rainer Volkamer
ResearchOpen Access14 Nov 2022
Nature Chemistry

Volume: 15, P: 129-135
A synthetic molecular pentafoil knot

The most complex non-DNA molecular knot prepared so far is self-assembled around a chloride anion from five metal cations, five bis-aldehyde and five bis-amine building blocks, in a one-pot reaction. The X-ray crystal structure of the 160-atom-loop pentafoil knot reveals a symmetrical closed-loop double helicate with a chloride anion held at its centre by ten CH···Cl⁻ hydrogen bonds.

Jean-François Ayme
Jonathon E. Beves
David Schultz
Research06 Nov 2011
Nature Chemistry

Volume: 4, P: 15-20
Association analyses identify 31 new risk loci for colorectal cancer susceptibility

In colorectal cancer (CRC), finding loci associated with risk may give insight into disease aetiology. Here, the authors report a genome-wide association analysis in Europeans of 34,627 CRC cases and 71,379 controls, and find 31 new risk loci and 17 new risk SNPs at previously reported loci.

Philip J. Law
Maria Timofeeva
Malcolm G. Dunlop
ResearchOpen Access14 May 2019
Nature Communications

Volume: 10, P: 1-15
The effect of acid–base clustering and ions on the growth of atmospheric nano-particles

The growth rates of freshly formed aerosol particles influence what fraction of these can reach sizes large enough to affect cloud formation and climate. Here, the authors show that the nano-particle growth in a sulphuric acid containing system can be enhanced by the presence of ions or small acid-base clusters.

Katrianne Lehtipalo
Linda Rondo
Markku Kulmala
ResearchOpen Access20 May 2016
Nature Communications

Volume: 7, P: 1-9
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Individual SNPs have small effects on anthropometric traits, yet the impact of CNVs has remained largely unknown. Here, Kutalik and co-workers perform a large-scale genome-wide meta-analysis of structural variation and find rare CNVs associated with height, weight and BMI with large effect sizes.

Aurélien Macé
Marcus A. Tuke
Zoltán Kutalik
ResearchOpen Access29 Sept 2017
Nature Communications

Volume: 8, P: 1-11
Distribution and heritability of BMI in Finnish adolescents aged 16 y and 17 y: A study of 4884 twins and 2509 singletons

KH Pietiläinen
J Kaprio
RJ Rose
Research25 Feb 1999
International Journal of Obesity

Volume: 23, P: 107-115
The Healthy Diet Basket is a valid global standard that highlights lack of access to healthy and sustainable diets

The Healthy Diet Basket (HDB) is used for the measurement of Cost and Affordability of a Healthy Diet globally. This analysis compares the economic, nutritional and environmental characteristics of least-cost diets following the HDB with national food-based dietary guidelines and the EAT-Lancet diet, demonstrating the use of the HDB as a global standard of healthy and sustainable diets.

Anna W. Herforth
Yan Bai
William A. Masters
ResearchOpen Access27 May 2025
Nature Food

Volume: 6, P: 622-631
Orlistat in responding obese type 2 diabetic patients: meta-analysis findings and cost-effectiveness as rationales for reimbursement in Sweden and Switzerland

J Ruof
A Golay
A Maetzel
Research01 Mar 2005
International Journal of Obesity

Volume: 29, P: 517-523
Health care costs of obesity in New Zealand

B Swinburn
T Ashton
J Birkbeck
Research01 Oct 1997
International Journal of Obesity

Volume: 21, P: 891-896
Physical activity patterns in normal, overweight and obese individuals using minute-by-minute accelerometry

AR Cooper
A Page
J Misson
Research27 Nov 2000
European Journal of Clinical Nutrition

Volume: 54, P: 887-894
Quercetin intake and the incidence of cerebrovascular disease

P Knekt
S Isotupa
A Reunanen
Research12 May 2000
European Journal of Clinical Nutrition

Volume: 54, P: 415-417
Rapid growth of new atmospheric particles by nitric acid and ammonia condensation

Measurements in the CLOUD chamber at CERN show that the rapid condensation of ammonia and nitric acid vapours could be important for the formation and survival of new particles in wintertime urban conditions, contributing to urban smog.

Mingyi Wang
Weimeng Kong
Neil M. Donahue
ResearchOpen Access13 May 2020
Nature

Volume: 581, P: 184-189
Primary breast sarcoma: clinicopathologic series from the Mayo Clinic and review of the literature

C Adem
C Reynolds
A G Nascimento
ResearchOpen Access08 Jun 2004
British Journal of Cancer

Volume: 91, P: 237-241
Systematic construction of progressively larger capsules from a fivefold linking pyrrole-based subcomponent

Controlling the self-assembly of large coordination cages is challenging owing to entropic costs and difficulties in error correction. Now an array of large cages prepared by the rational design of alterations that allow for the tuning of the dihedral angle between pentagonal subunits is reported.

Kai Wu
Tanya K. Ronson
Jonathan R. Nitschke
Research06 Apr 2023
Nature Synthesis

Volume: 2, P: 789-797
Infiltrated bunch of solitons in Bi-doped frequency-shifted feedback fibre laser operated at 1450 nm

Joona Rissanen
Dmitry A. Korobko
Regina Gumenyuk
ResearchOpen Access10 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
Hundreds of variants clustered in genomic loci and biological pathways affect human height

This very large genome-wide association study identifies hundreds of new genetic variants influencing adult height in at least 180 loci enriched for genes involved in skeletal growth defects. The results show that the likely causal gene is often located near the most strongly associated variant, that many loci have multiple independently associated variants and that associated variants are enriched for likely functional effects on genes.

Hana Lango Allen
Karol Estrada
Joel N. Hirschhorn
Research29 Sept 2010
Nature

Volume: 467, P: 832-838
Vascular endothelial growth factor D expression is a potential biomarker of bevacizumab benefit in colorectal cancer

A J Weickhardt
D S Williams
N C Tebbutt
ResearchOpen Access30 Jun 2015
British Journal of Cancer

Volume: 113, P: 37-45
Meta-analysis of the association of the Trp64Arg polymorphism in the β₃ adrenergic receptor with body mass index

DB Allison
M Heo
A Pietrobelli
Research09 Jun 1998
International Journal of Obesity

Volume: 22, P: 559-566
Haematological toxicity: a marker of adjuvant chemotherapy efficacy in stage II and III breast cancer

T Saarto
C Blomqvist
I Elomaa
Correspondence01 Jan 1997
British Journal of Cancer

Volume: 75, P: 301-305
Switchable protection and exposure of a sensitive squaraine dye within a redox active rotaxane

Incorporating sensitive chromophores into interlocked systems that are mechanically responsive to external stimuli is attractive for tuning of the dye’s optical properties and stability. Here, the authors report the mechanically controlled protection and deprotection of a squaraine dye within a [2]rotaxane, governed by macrocycle shielding/de-shielding upon chloride addition or oxidation.

Janos Wasternack
Hendrik V. Schröder
Christoph A. Schalley
ResearchOpen Access04 Oct 2024
Communications Chemistry

Volume: 7, P: 1-11
Identifying haplotype block structure using an ancestor-derived model

Hironori Fujisawa
Minoru Isomura
Masaaki Matsuura
Research01 Sept 2007
Journal of Human Genetics

Volume: 52, P: 738-746
Physical inactivity, sedentary lifestyle and obesity in the European Union

M Á Martínez-González
J Alfredo Martínez
J Kearney
Research11 Nov 1999
International Journal of Obesity

Volume: 23, P: 1192-1201
Weight change and blood coagulability and fibrinolysis in healthy obese women

P Rissanen
E Vahtera
A Rissanen
Research25 Mar 2001
International Journal of Obesity

Volume: 25, P: 212-218
Serum ceruloplasmin and the risk of cancer in Finland

P Knekt
A Aromaa
L Teppo
Research01 Feb 1992
British Journal of Cancer

Volume: 65, P: 292-296
Predictors of post-treatment weight reduction after in-patient behavioral therapy

U Cuntz
R Leibbrand
MM Fichter
Research01 May 2001
International Journal of Obesity

Volume: 25, P: S99-S101

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