Nature Search

Clinical genetic variation across Hispanic populations in the Mexican Biobank

Analyzing data of the Mexican Biobank project, a new study finds regional differences in clinically relevant genetic frequencies and presents MexVar, a publicly accessible resource designed to support ancestry-informed genetic testing.

Carmina Barberena-Jonas
Santiago G. Medina-Muñoz
Andrés Moreno-Estrada
ResearchOpen Access21 Jan 2026
Nature Medicine

P: 1-11
Specific types of male infertility are correlated with T cell exhaustion or senescence signatures

Whether male infertility is associated with specific immune alterations is still unclear. Here the authors use multiparameter phenotyping and single cell RNA sequencing to find that specific types of male infertility correlate with exhausted and senescent immune signatures in the blood, thereby hinting a personalized angle for male infertility management.

Giada Amodio
Giorgia Giacomini
Silvia Gregori
ResearchOpen Access24 Jan 2025
Nature Communications

Volume: 16, P: 1-17
Pathfinder experiments with atom interferometry in the Cold Atom Lab onboard the International Space Station

NASA’s Cold Atom Lab has operated on the International Space Station since 2018 to study quantum gases and mature quantum technologies in Earth’s orbit. Here, Williams et al., report on a series of pathfinding experiments exploring the first quantum sensor using atom interferometry in space.

Jason R. Williams
Charles A. Sackett
Nicholas P. Bigelow
ResearchOpen Access13 Aug 2024
Nature Communications

Volume: 15, P: 1-11
Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Increasing compositional uniqueness of the gut microbiome, and corresponding changes in microbial metabolites in the blood, are identified as a signature of healthy ageing in humans.

Tomasz Wilmanski
Christian Diener
Nathan D. Price
Research18 Feb 2021
Nature Metabolism

Volume: 3, P: 274-286
Mechanism of the Red Cell Changes in Non-hæJaundice

LIONEL BERK
Research03 Mar 1945
Nature

Volume: 155, P: 269-270
Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair

G4 structure-interacting proteins have been linked to DNA repair processes. Here the authors reveal that in yeast, Zuo1 associates with G4 structures and plays a role in repair pathway choice by promoting nucleotide excision repair and ultimately contributing to maintenance of genome stability.

Alessio De Magis
Silvia Götz
Katrin Paeschke
ResearchOpen Access06 Aug 2020
Nature Communications

Volume: 11, P: 1-12
Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling

Membrane-associated guanylate kinases (MAGUKs) are synaptic scaffold proteins involved in organizing protein complexes that are required for synaptic development and plasticity. Placing their focus on recent biochemical and structural data, Zhang and colleagues review the role of MAGUKs in synaptic protein complex formation and regulation.

Jinwei Zhu
Yuan Shang
Mingjie Zhang
Reviews18 Mar 2016
Nature Reviews Neuroscience

Volume: 17, P: 209-223
Health and disease markers correlate with gut microbiome composition across thousands of people

Variation in the gut microbiome can reflect host lifestyle, behaviour, and influence blood-based biomarkers. Here the authors examine associations between the microbiota and 150 host phenotypic features in a large cohort of >3,000 individuals.

Ohad Manor
Chengzhen L. Dai
Andrew T. Magis
ResearchOpen Access15 Oct 2020
Nature Communications

Volume: 11, P: 1-12
Seismic constraints from a Mars impact experiment using InSight and Perseverance

As the Perseverance rover landed on the Martian surface, the sensors on NASA’s InSight Mars lander picked up no seismic or acoustic waves. This non-detection provides information on the crust and atmosphere of Mars.

Benjamin Fernando
Natalia Wójcicka
Ingrid J. Daubar
ResearchOpen Access28 Oct 2021
Nature Astronomy

Volume: 6, P: 59-64
DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions

Translation efficiency can be affected by mRNA stability and secondary RNA structures. Here the authors reveal that loss of DHX36 helicase activity leads to an accumulation of translationally inactive target mRNAs with G-rich structures in untranslated regions.

Markus Sauer
Stefan A. Juranek
Katrin Paeschke
ResearchOpen Access03 Jun 2019
Nature Communications

Volume: 10, P: 1-15
Small-molecule Bax agonists for cancer therapy

A major proapoptotic mediator, Bax, is expressed in lung cancer and its activity can be regulated by phosphorylation. Here, the authors screen a library of compounds for their ability to alter the phosphorylation status of Bax and identify therapeutic candidates.

Meiguo Xin
Rui Li
Xingming Deng
Research17 Sept 2014
Nature Communications

Volume: 5, P: 1-11
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway

The homologous recombination machinery needs to be recruited at replication intermediates for accurate functioning. Here, the authors reveal that a Rad51 paralog-containing complex, called the Shu complex, recognizes and enables tolerance of predominantly lagging strand abasic sites.

Joel C. Rosenbaum
Braulio Bonilla
Kara A. Bernstein
ResearchOpen Access05 Aug 2019
Nature Communications

Volume: 10, P: 1-11
Author Correction: Gut microbiome pattern reflects healthy ageing and predicts survival in humans

Tomasz Wilmanski
Christian Diener
Nathan D. Price
Amendments and Corrections18 Mar 2021
Nature Metabolism

Volume: 3, P: 586
The atmosphere of Mars as observed by InSight

The InSight lander has expanded our knowledge of the atmosphere of Mars by observing various phenomena, including airglow, bores, infrasound and Earth-like turbulence.

Don Banfield
Aymeric Spiga
W. Bruce Banerdt
Research24 Feb 2020
Nature Geoscience

Volume: 13, P: 190-198
Geno4ME Study: implementation of whole genome sequencing for population screening in a large healthcare system

Isabelle A. Lucas Beckett
Kate R. Emery
Ora K. Gordon
ResearchOpen Access01 Jul 2025
npj Genomic Medicine

Volume: 10, P: 1-15
A fibered laser system for the MIGA large scale atom interferometer

D. O. Sabulsky
J. Junca
B. Canuel
ResearchOpen Access24 Feb 2020
Scientific Reports

Volume: 10, P: 1-14
Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineage-restricted chromatin-dependent and chromatin-independent regulatory elements

B Göttgens
F McLaughlin
A R Green
Research13 Nov 1997
Oncogene

Volume: 15, P: 2419-2428
Cluster headache

Cluster headache is characterized by unilateral headaches associated with ipsilateral autonomic features, such as lacrimation and rhinorrhoea. This Primer by May et al. discusses the pathophysiology, diagnosis and management of cluster headache in addition to the quality-of-life issues faced by patients.

Arne May
Todd J. Schwedt
Shuu-Jiun Wang
Reviews01 Mar 2018
Nature Reviews Disease Primers

Volume: 4, P: 1-17
Increased expression of receptor phosphotyrosine phosphatase-β/ζ is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes

N Takahashi
T Sakurai
J D Buxbaum
ResearchOpen Access10 May 2011
Translational Psychiatry

Volume: 1, P: e8
Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Laura Heath
John C. Earls
Yi Zhao
ResearchOpen Access12 Apr 2022
Scientific Reports

Volume: 12, P: 1-17
Identification of biomarkers for tuberculosis disease using a novel dual-color RT–MLPA assay

S A Joosten
J J Goeman
M C Haks
Research29 Sept 2011
Genes & Immunity

Volume: 13, P: 71-82
Habitual sleep duration and sleep duration variation are independently associated with body mass index

X Xu
M P Conomos
J C Lovejoy
Research12 Sept 2017
International Journal of Obesity

Volume: 42, P: 794-800

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