Nature Search

Thegosis in herbivorous dinosaurs

RICHARD A. THULBORN
Research30 Aug 1974
Nature

Volume: 250, P: 729-731
Opto-acoustic spectroscopy of products of continuous photolysis of nitromethane

M. J. COLLES
A. M. ANGUS
E. E. MARINERO
Research19 Aug 1976
Nature

Volume: 262, P: 681-683
Signalling by the sevenless protein tyrosine kinase is mimicked by Rasl activation

Mark E. Fortini
Michael A. Simon
Gerald M. Rubin
Research06 Feb 1992
Nature

Volume: 355, P: 559-561
DNA methylation enzymes and PRC1 restrict B-cell Epstein–Barr virus oncoprotein expression

A CRISPR–Cas9 screening identifies cellular genes that regulate Epstein–Barr virus latency type I–III transition. The authors identify UHRF1 and DNMT1 as major regulators of this pathway. They also show that components of the polycomb repressor complex contribute to this regulation.

Rui Guo
Yuchen Zhang
Benjamin E. Gewurz
Research18 May 2020
Nature Microbiology

Volume: 5, P: 1051-1063
Stable carbon isotope variation in C₃ and C₄ plants along the Amazon River

Luiz A. Martinelli
Allan H. Devol
Jeffrey E. Richey
Research05 Sept 1991
Nature

Volume: 353, P: 57-59
Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination

Oliver Smithies
Ronald G. Gregg
Raju S. Kucherlapati
Research19 Sept 1985
Nature

Volume: 317, P: 230-234
Loss of KLF14 triggers centrosome amplification and tumorigenesis

Centrosome amplification is common in cancer, but the mechanism is not clear. Here the authors uncover a role for Kruppel-like factor 14 (KLF14) as a transcriptional repressor of polo-like kinase 4 (PLK4); KLF14 depletion correlates with increased PLK4 in human samples and leads to centrosome amplification and tumorigenesis in mice.

Guangjian Fan
Lianhui Sun
Chuangui Wang
ResearchOpen Access06 Oct 2015
Nature Communications

Volume: 6, P: 1-13
Dual character of the rapid burster and a classification of X-ray bursts

JEFFREY A. HOFFMAN
HERMAN L. MARSHALL
WALTER H. G. LEWIN
Research16 Feb 1978
Nature

Volume: 271, P: 630-633
Mostly Mammals Zoological Essays

J. A. T.
Books & Arts14 Apr 1904
Nature

Volume: 69, P: 554-556
Hot and Hungry - High temperatures induce changes in leaf carbon dynamics and sugar isotope fingerprints

Philipp Schuler
Margaux Didion-Gency
Marco M. Lehmann
ResearchOpen Access01 Dec 2025
npj Science of Plants

Volume: 1, P: 1-12
Protein-primed homopolymer synthesis by an antiviral reverse transcriptase

A bacterial reverse transcriptase synthesizes polydeoxyadenylate to provide population-level immunity against viral infection.

Stephen Tang
Rimantė Žedaveinytė
Samuel H. Sternberg
Research28 May 2025
Nature

Volume: 643, P: 1352-1362
MAPS: pathologist-level cell type annotation from tissue images through machine learning

Current cell annotation methods using high-plex spatial proteomics data are resource intensive and demand iterative expert input. Here, the authors present MAPS (Machine learning for Analysis of Proteomics in Spatial biology), an approach that facilitates rapid and precise cell type identification with human-level accuracy from spatial proteomics data.

Muhammad Shaban
Yunhao Bai
Faisal Mahmood
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-11
A novel scoring system for TIGIT expression in classic Hodgkin lymphoma

Ombretta Annibali
Antonella Bianchi
Anna Crescenzi
ResearchOpen Access29 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Human artificial episomal chromosomes for cloning large DNA fragments in human cells

Tian-Qiang Sun
David A. Fenstermacher
Jean-Michel H. Vos
Research01 Sept 1994
Nature Genetics

Volume: 8, P: 33-41
Conversation in AI

John A. Campbell
Books & Arts27 Feb 1986
Nature

Volume: 319, P: 798
A diffusion–collision–adhesion model for the kinetics of myoglobin refolding

F. E. Cohen
M. J. E. Sternberg
P. A. Kollman
Research07 Aug 1980
Nature

Volume: 286, P: 632-634
Unraveling the glycosylated immunopeptidome with HLA-Glyco

Protein glycosylation plays a vital role in antigen recognition and immune modulation. Here, the authors present a computational workflow for identifying glycosylated peptides from mass spectrometry-based immunopeptidome data and investigate the properties of glycosylated MHC associated peptides.

Georges Bedran
Daniel A. Polasky
Alexey I. Nesvizhskii
ResearchOpen Access12 Jun 2023
Nature Communications

Volume: 14, P: 1-12
Ultrasonic Absorption in Liquids from Thermal Steady States

S. PARTHASARATHY
S. S. MATHUR
Research18 Aug 1956
Nature

Volume: 178, P: 378-379
Is contrast-enhanced CT necessary for following up NMIBC?

Although patients with bladder cancer are at increased risk of developing upper tract urothelial carcinoma (UTUC), the overall incidence remains low. Serial CT urography is routinely performed in these patients to rule out UTUC, but its clinical value and cost-effectiveness are questionable, especially in patients with non-muscle-invasive disease.

Mesut Remzi
Shahrokh F. Shariat
News & Views06 Aug 2013
Nature Reviews Urology

Volume: 10, P: 500-501
Myxoinflammatory fibroblastic sarcoma: an immunohistochemical and molecular genetic study of 73 cases

David Suster
Michael Michal
A. Craig Mackinnon
Research08 Jun 2020
Modern Pathology

Volume: 33, P: 2520-2533
A physical map and candidate genes in the BRCA1 region on chromosome 17q12–21

H.M. Albertsen
S. A. Smith
Ray White
Research01 Aug 1994
Nature Genetics

Volume: 7, P: 472-479
Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography

Titia K. Sixma
SyMa E. Pronk
Wim G. J. Hol
Research06 Feb 1992
Nature

Volume: 355, P: 561-564
MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Detection of neoepitopes from tumours is time consuming and requires the integration of genomic and/or RNA sequencing expression data. Here, the authors propose a machine learning method to enable direct identification of additional, tumour-specific sequences using mass spectrometry through integration of de novo peptide sequencing scores, MHC class I binding prediction, and peptide retention time prediction.

Hanqing Liao
Carolina Barra
Nicola Ternette
ResearchOpen Access22 Jan 2024
Nature Communications

Volume: 15, P: 1-16
The Dual Mechanisms of Cognitive Control dataset, a theoretically-guided within-subject task fMRI battery

Joset A. Etzel
Rachel E. Brough
Todd S. Braver
ResearchOpen Access29 Mar 2022
Scientific Data

Volume: 9, P: 1-14
Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation

A germline variant associated with acute lymphoblastic leukemia activates an enhancer element resulting in increased GATA3 expression, altered chromatin accessibility and changes in three-dimensional genome organization.

Hongbo Yang
Hui Zhang
Jun J. Yang
Research03 Feb 2022
Nature Genetics

Volume: 54, P: 170-179
The C1q receptor site on immunoglobulin G

D. R. Burton
J. Boyd
R. A. Dwek
Research27 Nov 1980
Nature

Volume: 288, P: 338-344
Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules

Proteins evolve through the modular rearrangement of domains. Here the authors introduce MISER, a minimization by iterative size-exclusion and recombination method to make all possible deletions of a protein, uncovering functions for Cas9 domains involved in DNA binding.

Arik Shams
Sean A. Higgins
David F. Savage
ResearchOpen Access27 Sept 2021
Nature Communications

Volume: 12, P: 1-11
Genetic loci influencing kidney function and chronic kidney disease

John Chambers and colleagues identify common variants at four loci associated with serum creatinine levels, a marker of kidney function. Their findings provide insight into the pathways underlying susceptibility to chronic kidney disease.

John C Chambers
Weihua Zhang
Jaspal S Kooner
Research11 Apr 2010
Nature Genetics

Volume: 42, P: 373-375
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

Neoantigens determine anti-cancer immunoreactivity and are important functional targets for immunotherapy. Here, the authors use deep mass spectrometry to characterize neoepitopes from human melanoma tissue and show the presence of tumour-reactive T cells with specificity for selected neoantigens.

Michal Bassani-Sternberg
Eva Bräunlein
Angela M. Krackhardt
ResearchOpen Access21 Nov 2016
Nature Communications

Volume: 7, P: 1-16
Genome dependent Cas9/gRNA search time underlies sequence dependent gRNA activity

The link between gRNA sequence and Cas9 activity is well established but the mechanism underlying this relationship is not well understood. Here the authors show that gRNA sequence primarily influences activity by dictating the time it takes for Cas9 to find the target site in a species-specific manner.

E. A. Moreb
M. D. Lynch
ResearchOpen Access19 Aug 2021
Nature Communications

Volume: 12, P: 1-13
A Siderite of the Fourteenth Century

MOHD. A. R. KHAN
Research07 Oct 1944
Nature

Volume: 154, P: 465
A Hydrogen Singing-flame Ionization Detector

L. B. GRAIFF
Research22 Aug 1964
Nature

Volume: 203, P: 856
Diperoxodiethylenetriamminechromium(IV) 1-hydrate: a New Chromium(IV) Peroxo Compound

D. A. HOUSE
CLIFFORD S. GARNER
Research20 Nov 1965
Nature

Volume: 208, P: 776-777
Automatic alerting does not speed late motoric processes in a reaction-time task

Steven A. Hackley
Fernando Valle-Inclán
Research19 Feb 1998
Nature

Volume: 391, P: 786-788
Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors

Malignant pleural mesothelioma is an aggressive cancer with a poor prognosis and limited therapeutic options. Here the authors report the immunopeptidomic landscape of murine and human mesothelioma tumors and demonstrate the anti-tumor potential of oncolytic adenoviruses coated with so-defined tumor-specific peptides in a mouse model of mesothelioma.

Jacopo Chiaro
Gabriella Antignani
Vincenzo Cerullo
ResearchOpen Access03 Nov 2023
Nature Communications

Volume: 14, P: 1-16
Multidisciplinary management of bone complications in prostate cancer and optimizing outcomes of bisphosphonate therapy

Fred Saad
Cora N Sternberg
Research01 Feb 2007
Nature Clinical Practice Urology

Volume: 4, P: S3-S13
Experimental and computational framework for a dynamic protein atlas of human cell division

Quantitative live-cell imaging provides a dynamic protein atlas of mitosis.

Yin Cai
M. Julius Hossain
Jan Ellenberg
Research10 Sept 2018
Nature

Volume: 561, P: 411-415
Transcriptional reprogramming by mutated IRF4 in lymphoma

Cancer is often associated with mutant transcription factors (TFs) but their functional characterization is challenging. Here, the authors describe a recurrent mutation within TF IRF4 in human lymphomas and they show how it causes a complex switch in TF specificity and functionality.

Nikolai Schleussner
Pierre Cauchy
Stephan Mathas
ResearchOpen Access07 Nov 2023
Nature Communications

Volume: 14, P: 1-18
Complete Ichthyornis skull illuminates mosaic assembly of the avian head

High-resolution computed tomography of three-dimensionally preserved specimens of Ichthyornis dispar clarifies the mosaic evolution of the avian head, revealing a kinetic feeding apparatus reminiscent of modern birds, a transitional beak and a dinosaurian temporal region.

Daniel J. Field
Michael Hanson
Bhart-Anjan S. Bhullar
Research02 May 2018
Nature

Volume: 557, P: 96-100
Isolation by molecular cloning of a fragment of the split ovalbumin gene

A. C. Garapin
J. P Lepennec
P. Kourilsky
Research01 Jun 1978
Nature

Volume: 273, P: 349-354
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus

While Hodgkin lymphoma (HL) is a common cancer affecting young adults in Western countries, its genetic basis is poorly understood. Here, the authors carry out a genome-wide association analysis in HL patients and healthy controls; identifying a new HL risk locus and implicating TCF3in the disease aetiology.

W. Cozen
M. N. Timofeeva
J. D. McKay
Research12 Jun 2014
Nature Communications

Volume: 5, P: 1-10
Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA

Engineered high-fidelity Cas9s have increased discrimination against off-targets. Kinetic analyses of Cas9-HF1 and HypaCas9 engineered Cas9 variants show that their DNA cleavage is impaired by more than 100- fold, which leads to release rather than cleavage of a bound off-target substrate.

Mu-Sen Liu
Shanzhong Gong
David W. Taylor
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-13
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system

Lolo et al. show caveolin-1 functions in non-caveolae structures termed dolines. Whereas caveolae respond to high forces over a mechanical threshold, dolines transduce low and medium mechanical forces gradually in a complementary buffering system.

Fidel-Nicolás Lolo
Nikhil Walani
Miguel A. del Pozo
ResearchOpen Access21 Dec 2022
Nature Cell Biology

Volume: 25, P: 120-133
Crystal structure of an HIV-binding recombinant fragment of human CD4

Seong-Eon Ryu
Peter D. Kwong
Wayne A. Hendrickson
Research29 Nov 1990
Nature

Volume: 348, P: 419-426
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

Ming Y. Cheng
F.-Ulrich Hartl
Arthur L. Horwich
Research16 Feb 1989
Nature

Volume: 337, P: 620-625
Far Infra-red Spectroscopy at High Pressures

C. C. BRADLEY
H. A. GEBBIE
J. H. KING
Research20 Aug 1966
Nature

Volume: 211, P: 839-840
Globular Clusters as Remnants of Quasars

ARNE A. WYLLER
Research24 Jul 1965
Nature

Volume: 207, P: 394-395
The mechanism of calcium ionophore-induced secretion from the rat neurohypophysis

J. J. NORDMANN
GLYNIS A. CURRELL
Research01 Feb 1975
Nature

Volume: 253, P: 646-647
Sub-sieve Sizing by Sedimentation Balance

C. C. HARRIS
A. JOWETT
Research23 Mar 1963
Nature

Volume: 197, P: 1192-1193
Faeces of the Medicinal Leech, Hirudo medicinalis, are Haem

DONALD A. WINDSOR
Research12 Sept 1970
Nature

Volume: 227, P: 1153-1154

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