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Showing 1–7 of 7 results
Advanced filters: Author: Abigail K. D. Porter Clear advanced filters

  • The enzyme PCMT1 was found to install a C-terminal cyclic imide modification on proteins that marks them for degradation by CRBN, uncovering a conserved protein turnover pathway with implications in metabolism and neurological function.

    • Zhenguang Zhao
    • Wenqing Xu
    • Christina M. Woo
    Research
    Nature Chemical Biology
    P: 1-11

  • How the development of the cochlear epithelium is regulated is unclear. Here, the authors use single cell RNAseq analysis to provide insight into the transcriptional changes arising during development of the murine cochlear inner and outer hair cells.

    • Likhitha Kolla
    • Michael C. Kelly
    • Matthew W. Kelley
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16

  • In studies using mouse models of psoriasis, a spectrum of innate lymphoid cell types is reconfigured and converges via multiple trajectories on a type 3-like state, demonstrating the range and flexibility of innate lymphoid cell responses in the skin.

    • Piotr Bielecki
    • Samantha J. Riesenfeld
    • Richard A. Flavell
    Research
    Nature
    Volume: 592, P: 128-132

  • Single-cell RNA sequencing analysis of over 800,000 human adult breast cells from 55 female donors identifies 41 cell subtypes and highlights age- and parity-dependent effects. Samples from healthy women with germline mutations in BRCA1 or BRCA2 showed signs of T cell exhaustion.

    • Austin D. Reed
    • Sara Pensa
    • Walid T. Khaled
    ResearchOpen Access
    Nature Genetics
    Volume: 56, P: 652-662

  • Here, the authors show that real-world extraordinary altruists, including heroic rescuers and altruistic kidney donors, are distinguished by unusually unselfish traits and decision-making patterns. This pattern was not predicted by a general sample of adults who were asked what traits would characterize altruists.

    • Shawn A. Rhoads
    • Kruti M. Vekaria
    • Abigail A. Marsh
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Data on the nutrient content of almost 3,000 aquatic animal-source foods is combined with a food-systems model to show that an increase in aquatic-food production could reduce the inadequate intake of most nutrients.

    • Christopher D. Golden
    • J. Zachary Koehn
    • Shakuntala H. Thilsted
    Research
    Nature
    Volume: 598, P: 315-320