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Showing 1–50 of 80 results

Advanced filters: Author: Alan J. Kaufman Clear advanced filters

Electrophoretic Pattern of Lactic Dehydrogenase in Carriers and Patients with Duchenne Muscular Dystrophy

ALAN E. H. EMERY
Research07 Mar 1964
Nature

Volume: 201, P: 1044-1045
Evidence for a Junctional Effect of Lead on Neuromuscular Function

ELLEN K. SILBERGELD
JOHN T. FALES
ALAN M. GOLDBERG
Research04 Jan 1974
Nature

Volume: 247, P: 49-50
An ice age in the tropics

Alan J. Kaufman
News & Views20 Mar 1997
Nature

Volume: 386, P: 227-228
Graphite–magnetite aggregates in ordinary chondritic meteorites

Edward R. D. Scott
G. Jeffrey Taylor
Klaus Keil
Research18 Jun 1981
Nature

Volume: 291, P: 544-546
Production of RNA for secreted immunoglobulin μ chains does not require transcriptional termination 5′ to the μ_M exons

David J. Kemp
Grant Morahan
Alan W. Harris
Research06 Jan 1983
Nature

Volume: 301, P: 84-86
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes–prone mice

Jide Tian
Michael Clere-Salzler
Daniel L. Kaufman
Research01 Dec 1996
Nature Medicine

Volume: 2, P: 1348-1353
Cloned human phenylalanine hydroxylase gene allows prenatal diagnosis and carrier detection of classical phenylketonuria

Savio L. C. Woo
Alan S. Lidsky
Kathryn J. H. Robson
Research10 Nov 1983
Nature

Volume: 306, P: 151-155
Uniformity of Radiation-induced Mutation Rates among Different Species

SEYMOUR ABRAHAMSON
MICHAEL A. BENDER
SHELDON WOLFF
Research26 Oct 1973
Nature

Volume: 245, P: 460-462
Murine Hybridoma Antibodies Enhance Bactericidal Activity of Human Cord Blood against K1 Escherichia coli Strains

Kwang Sik Kim
Alan S Cross
Jerald Sadof
Research01 Dec 1990
Pediatric Research

Volume: 28, P: 667-670
HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper
Kate Hardy
Marilyn Monk
Research25 Mar 1987
Nature

Volume: 326, P: 292-295
Deep structure of the Scottish Caledonides revealed by the MOIST reflection profile

David K. Smythe
Alan Dobinson
Brian Kelk
Research23 Sept 1982
Nature

Volume: 299, P: 338-340
Biochemical Research in Schizophrenia

ALAN A. BOULTON
Research07 May 1971
Nature

Volume: 231, P: 22-28
Determinant selection is a macrophage dependent immune response gene function

ALAN S. ROSENTHAL
MARCELLO A. BARCINSKI
J. THOMAS BLAKE
Research12 May 1977
Nature

Volume: 267, P: 156-158
Requirement for a functional Rb-1 gene in murine development

Alan R. Clarke
Els Robanus Maandag
Hein te Rielef
Research24 Sept 1992
Nature

Volume: 359, P: 328-330
Calibration of the ¹⁴C timescale over the past 30,000 years using mass spectrometric U–Th ages from Barbados corals

Edouard Bard
Bruno Hamelin
Alan Zindler
Research31 May 1990
Nature

Volume: 345, P: 405-410
Drug-induced ocular cicatricial pemphigoid: A series of clinico-pathological reports

Zahida Butt
David Kaufman
Penny McKelvie
Research01 Mar 1998
Eye

Volume: 12, P: 285-290
Androgen-Receptor Blockade Enhances Pulsatile Luteinizing Hormone Production in Late Pubertal Males: Evidence for a Hypothalamic Site of Physiologic Androgen Feedback Action

James R Kerrigan
Johannes D Veldhuis
Alan D Rogol
Research01 Jan 1994
Pediatric Research

Volume: 35, P: 102-106
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc

Manfred Schwab
Harold E. Varmus
Jeffrey Trent
Research15 Mar 1984
Nature

Volume: 308, P: 288-291
Cloning and expression in E. coli of the malarial sporozoite surface antigen gene from Plasmodium knowlesi

Joan Ellis
Luiz S. Ozaki
G. Nigel Godson
Research01 Apr 1983
Nature

Volume: 302, P: 536-538
Pervasive oxygenation along late Archaean ocean margins

The photosynthetic production of oxygen in the ocean is thought to have begun at least 2.7 billion years ago. The geochemistry of marine sediments deposited 2.6 billion years ago suggests that ocean margins were oxygenated at least 100 million years before the first significant increase in atmospheric oxygen concentrations.

Brian Kendall
Christopher T. Reinhard
Ariel D. Anbar
Research22 Aug 2010
Nature Geoscience

Volume: 3, P: 647-652
Polygenic and developmental profiles of autism differ by age at diagnosis

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

Xinhe Zhang
Jakob Grove
Varun Warrier
ResearchOpen Access01 Oct 2025
Nature

Volume: 646, P: 1146-1155
Author Correction: Basin-scale reconstruction of euxinia and Late Devonian mass extinctions

Swapan K. Sahoo
Geoffrey J. Gilleaudeau
Alan J. Kaufman
Amendments and Corrections05 Apr 2023
Nature

Volume: 617, P: E6
Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non–permissive genetic background

Jim McWhir
Angelika E. Schnieke
Alexander J. Kind
Research01 Oct 1996
Nature Genetics

Volume: 14, P: 223-226
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Shilpa Nadimpalli Kobren
Mikhail A. Moldovan
Shamil R. Sunyaev
ResearchOpen Access07 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Functional diversity of helper T lymphocytes

Abul K. Abbas
Kenneth M. Murphy
Alan Sher
Reviews31 Oct 1996
Nature

Volume: 383, P: 787-793
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

Stephen C. Hyde
Deborah R. Gill
William H. Colledge
Research18 Mar 1993
Nature

Volume: 362, P: 250-255
Basin-scale reconstruction of euxinia and Late Devonian mass extinctions

A spatial and temporal compilation of geochemical data documents a stepwise transgression of toxic euxinic waters into shallow oceans that drove a series of Late Devonian extinction events.

Swapan K. Sahoo
Geoffrey J. Gilleaudeau
Alan J. Kaufman
Research08 Mar 2023
Nature

Volume: 615, P: 640-645
Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Richard J. Gregory
Seng H. Cheng
Alan E. Smith
Research27 Sept 1990
Nature

Volume: 347, P: 382-386
No female embryonic lethality in mice nullizygous for Msh2 and p53

Neil J. Toft
Mark J. Arends
Alan R. Clarke
Correspondence01 Jan 1998
Nature Genetics

Volume: 18, P: 17
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Multi-ancestry genome-wide analyses identify 95 loci associated with post-traumatic stress disorder and implicate candidate genes, pathways and neurobiological systems underlying its pathophysiology.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
Research18 Apr 2024
Nature Genetics

Volume: 56, P: 792-808
Measurement of Cardiopulmonary Function in Ventilated Neonates with Respiratory Distress Syndrome Using Rebreathing Methodology

Carl L Bose
Edward E Lawson
Mitchell Friedman
Research01 Apr 1986
Pediatric Research

Volume: 20, P: 316-320
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders

How neurodevelopmental disorder-associated risk genes are translated into spatially patterned brain vulnerabilities is unclear. Here, the authors show that disorder-specific patterns of neuroanatomical changes are aligned to brain expression maps of disease risk genes in healthy subjects.

Jakob Seidlitz
Ajay Nadig
Armin Raznahan
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-14
Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses

Study shows PTSD predisposition shares distinct genes and genomic regions with several cardiovascular conditions. Here the findings reveal neuronal, immune, and metabolic pathways, and repurposed drug targets that further the understanding of the comorbidity.

Jie Shen
Wander Valentim
Gita A. Pathak
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
A deep catalogue of protein-coding variation in 983,578 individuals

A dataset of coding variation, derived from exome sequencing of nearly one million individuals from a range of ancestries, provides insight into rare variants and could accelerate the discovery of disease-associated genes and advance precision medicine efforts.

Kathie Y. Sun
Xiaodong Bai
Suganthi Balasubramanian
ResearchOpen Access20 May 2024
Nature

Volume: 631, P: 583-592
Atomic-beam alignment of inorganic materials for liquid-crystal displays

P. Chaudhari
James Lacey
Yasuhiko Shiota
Research03 May 2001
Nature

Volume: 411, P: 56-59
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Genome-wide association meta-analyses among 1.4 million individuals identify 318 new risk loci for type 2 diabetes and provide insight into the contribution of these risk variants to diabetes-related vascular outcomes.

Marijana Vujkovic
Jacob M. Keaton
Danish Saleheen
Research15 Jun 2020
Nature Genetics

Volume: 52, P: 680-691
Thymidine kinase gene therapy with concomitant topotecan chemotherapy for recurrent ovarian cancer

Annette Hasenburg
Xiao-Wen Tong
Dirk G Kieback
Research15 Jun 2000
Cancer Gene Therapy

Volume: 7, P: 839-844
A single-blind active-control randomized controlled trial of group-based social competence intervention

Erin Kang
Tamara E. Rosen
Matthew D. Lerner
ResearchOpen Access07 Aug 2025
Scientific Reports

Volume: 15, P: 1-11
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Post-traumatic stress disorder (PTSD) is a common mental health problem. Here, the authors report a GWAS from the Psychiatric Genomics Consortium in which they identify two risk loci in European ancestry and one locus in African ancestry individuals and find that PTSD is genetically correlated with several other psychiatric traits.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
ResearchOpen Access08 Oct 2019
Nature Communications

Volume: 10, P: 1-16
High CO₂ levels in the Proterozoic atmosphere estimated from analyses of individual microfossils

Alan J. Kaufman
Shuhai Xiao
Research18 Sept 2003
Nature

Volume: 425, P: 279-282
Complement genes contribute sex-biased vulnerability in diverse disorders

Sexual dimorphism in genetic vulnerability to schizophrenia, systemic lupus erythematosus and Sjögren’s syndrome is linked to differential protein abundance from alleles of complement component 4.

Nolan Kamitaki
Aswin Sekar
Steven A. McCarroll
Research11 May 2020
Nature

Volume: 582, P: 577-581
Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome

Carmen C Leitch
Norann A Zaghloul
Nicholas Katsanis
Research09 Mar 2008
Nature Genetics

Volume: 40, P: 443-448
Cyanobacteria at work

Oxygen-producing photosynthesis must have evolved before the pervasive oxidation of the atmosphere around 2.4 billion years ago, but how long before is unclear. Geochemical analyses of ancient sedimentary rocks now suggest that cyanobacteria generated oxygen at least 3 billion years ago.

Alan J. Kaufman
News & Views23 Mar 2014
Nature Geoscience

Volume: 7, P: 253-254
Identification of the gene that, when mutated, causes the human obesity syndrome BBS4

Kirk Mykytyn
Terry Braun
Val C. Sheffield
Research01 Jun 2001
Nature Genetics

Volume: 28, P: 188-191
Emerging roles of caspase-3 in apoptosis

Alan G Porter
Reiner U Jänicke
Reviews28 Jan 1999
Cell Death & Differentiation

Volume: 6, P: 99-104
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy

RNA-based viruses can be engineered to express artificial microRNAs (amiRNAs). Here, the authors identify a candidate amiRNA that confers a replicative advantage to oncolytic viruses, enhancing their anticancer potency, and show that intercellular transfer of extracellular vesicles carrying the amiRNA promotes bystander killing of uninfected cancer cells.

Marie-Eve Wedge
Victoria A. Jennings
Carolina S. Ilkow
ResearchOpen Access07 Apr 2022
Nature Communications

Volume: 13, P: 1-16
EFFICACY OF VARIOUS MONOCLONAL ANTIBODIES (Ab) AGAINST E. COLI (EC)

Kwang Sik Kim
Daisy Green
Michael Apicella
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 279
A diverse Ediacara assemblage survived under low-oxygen conditions

Geochemical data from sedimentary rocks in Siberia indicate that members of the soft-bodied Ediacara biota (the earliest macroscopic life on Earth) were tolerant of low-oxygen conditions, suggesting they had the capacity for anaerobic metabolisms.

Lucas B. Cherry
Geoffrey J. Gilleaudeau
Alan J. Kaufman
ResearchOpen Access27 Nov 2022
Nature Communications

Volume: 13, P: 1-11
Isotopic evidence for Mesoarchaean anoxia and changing atmospheric sulphur chemistry

The observation of non-mass-dependent sulphur isotope ratios in sedimentary rocks more than ∼2.4 billion years old and the disappearance of this signal in younger sediments is taken as evidence for the transition from an anoxic to oxic atmosphere around 2.4 Gyr ago. But now, the preservation of a non mass-dependent signal that differs from that of preceding and following periods in the Archean is demonstrated. The findings support the original idea of an anoxic early atmosphere before 2.4 Gyr ago, and at the same time identifies variability within the isotope record that suggests changes in pre-2.4 Gya atmospheric pathways for non-mass-dependent chemistry and in the ultraviolet transparency of an evolving early atmosphere.

James Farquhar
Marc Peters
Alan J. Kaufman
Research11 Oct 2007
Nature

Volume: 449, P: 706-709

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