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Showing 1–3 of 3 results
Advanced filters: Author: Albert Fradera-Sola Clear advanced filters

  • ZNF524 is a newly described protein that binds to telomeres, the ends of linear chromosomes. ZNF524 promotes the presence of two members of the shelterin complex, TRF2/RAP1, at telomeres, and prevents genomic instability.

    • Hanna Braun
    • Ziyan Xu
    • Dennis Kappei
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Telomeres, tandem repeats at the ends of linear chromosomes, have evolved to deal with the end replication and end protection. Using a proteomics approach, the authors identify TEBP-1 and TEBP-2, two double-stranded binding proteins which together are required for fertility. Despite being paralogs, they have distinct individual effects on telomere dynamics; TEBP-1 and TEBP-2 are part of a telomeric complex also containing POT-1.

    • Sabrina Dietz
    • Miguel Vasconcelos Almeida
    • Falk Butter
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-20

  • The regulation of Mtfp1 by the transcription factor Zbtb48 is evolutionary conserved within vertebrates.

    • Goh Sho Yee Carisa
    • Albert Fradera-Sola
    • Falk Butter
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-12