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Showing 1–2 of 2 results
Advanced filters: Author: Alberto Sada Japp Clear advanced filters

  • The status of immune cells within human pancreatic lymphatic tissues during the onset and progression of type 1 diabetes (T1D) is underexplored. Here, by flow cytometry and CITEseq, the authors profile pancreatic, mesenteric, and splenic lymphatic tissues from individuals with varying clinical statuses and identify tissue-specific immune responses associated with T1D autoimmunity.

    • Gregory J. Golden
    • Vincent H. Wu
    • Michael R. Betts
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Peptide-MHC (pMHC) tetramers are important tools for probing T cell repertoire and adaptive immune responses. Here the authors use a molecular chaperone, TAPBPR, to develop a high-throughput, multiplexible platform for pMHC tetramer generation to facilitate simultaneous assessments of T cell repertoire/antigen specificity and transcriptome.

    • Sarah A. Overall
    • Jugmohit S. Toor
    • Nikolaos G. Sgourakis
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13