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Activity of Classical and Alternative Pathways of Complement in Preterm and Small for Gestational Age Infants

Luigi D Notarangelo
Gaetano Chirico
Alberto G Ugazio
Research01 Mar 1984
Pediatric Research

Volume: 18, P: 281-285
Correction: Corrigendum: B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Irene Puga
Montserrat Cols
Andrea Cerutti
Amendments and Corrections21 Jan 2014
Nature Immunology

Volume: 15, P: 205
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

Immunoglobulin class-switch recombination can be induced by the secreted factors BAFF and APRIL. Cerutti and colleagues show that the receptor TACI conveys such signals via the adaptor MyD88 to induce class-switch recombination.

Bing He
Raul Santamaria
Andrea Cerutti
Research01 Aug 2010
Nature Immunology

Volume: 11, P: 836-845
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly

Loss of the cadherin FAT1 has been associated with nephropathy and epithelial cell adhesion defects. Here, the authors report five families with a syndromic form of coloboma associated with homozygous frameshift variants in FAT1 and recapitulate the phenotype in mutant mice and zebrafish.

Najim Lahrouchi
Aman George
Abdelaziz Sefiani
ResearchOpen Access12 Mar 2019
Nature Communications

Volume: 10, P: 1-11
Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Haifa H. Jabara
Douglas R. McDonald
Raif S. Geha
Amendments and Corrections24 Mar 2022
Nature Immunology

Volume: 23, P: 815
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Dock8 deficiency leads to defects in humoral immunity. Geha and colleagues show that Dock88 interacts with MyD88 to bridge TLR9 signaling to the Src-Syk-STAT3 pathway to promote B cell proliferation and differentiation.

Haifa H Jabara
Douglas R McDonald
Raif S Geha
Research13 May 2012
Nature Immunology

Volume: 13, P: 612-620
Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophils

Mature B cells express immunoglobulin D, but its function is unknown. Cerutti and colleagues show that respiratory mucosal B cells secrete immunoglobulin D, which activates basophils and enhances antimicrobial function.

Kang Chen
Weifeng Xu
Andrea Cerutti
Research28 Jun 2009
Nature Immunology

Volume: 10, P: 889-898
B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Follicular T cells provide help to B cells to elicit antibody responses. Cerutti and colleagues show that neutrophils provide help to marginal-zone B cells that produce T cell–independent antibodies.

Irene Puga
Montserrat Cols
Andrea Cerutti
Research25 Dec 2011
Nature Immunology

Volume: 13, P: 170-180
Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

Paola Bronson, Lennart Hammarström and colleagues report a genome-wide association study meta-analysis of selective IgA immunodeficiency in Europeans. They identify four new loci and a rare variant of a previously associated gene, IFIH1.

Paola G Bronson
Diana Chang
Timothy W Behrens
Research10 Oct 2016
Nature Genetics

Volume: 48, P: 1425-1429
A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly

Nagaja Capitani
Anna Onnis
Cosima T. Baldari
Research22 Jul 2021
Cell Death & Differentiation

Volume: 29, P: 65-81
Linkage of autosomal-dominant common variable immunodeficiency to chromosome 4q

Anemone Finck
Jos W M Van der Meer
Bodo Grimbacher
Research26 Apr 2006
European Journal of Human Genetics

Volume: 14, P: 867-875

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Activity of Classical and Alternative Pathways of Complement in Preterm and Small for Gestational Age Infants

Correction: Corrigendum: B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly

Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell–stimulating programs in basophils

B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly

Linkage of autosomal-dominant common variable immunodeficiency to chromosome 4q

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