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Nature Methods (2)
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Showing 1–3 of 3 results

Advanced filters: Author: Alexander W. Senko Clear advanced filters

Decoding the protein composition of whole nucleosomes with Nuc-MS

Nuc-MS makes use of top–down mass spectrometry in ‘native’ mode to quantitatively interrogate histone proteoforms and their post-translational modifications in a single experiment.

Luis F. Schachner
Kevin Jooß
Neil L. Kelleher
Research15 Feb 2021
Nature Methods

Volume: 18, P: 303-308
Remotely controlled chemomagnetic modulation of targeted neural circuits

Controlled delivery of neuromodulators in the brain might improve the understanding of the molecular basis of behaviour. In this letter, magnetic liposomes injected in deep brain regions release small molecules under remote magnetic stimulation, activating specific neuronal circuits in freely moving mice.

Siyuan Rao
Ritchie Chen
Polina Anikeeva
Research19 Aug 2019
Nature Nanotechnology

Volume: 14, P: 967-973
Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes

Charge assignment for individual ions unlocks complex mixtures of proteoforms and their assemblies by native mass spectrometry.

Jared O. Kafader
Rafael D. Melani
Neil L. Kelleher
Research02 Mar 2020
Nature Methods

Volume: 17, P: 391-394