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Showing 1–4 of 4 results
Advanced filters: Author: Alice Bertocchi Clear advanced filters

  • T helper 17 (TH17) cells can have both pro-tumour and antitumour effects. Understanding how they are regulated by environmental and regulatory cues according to context will inform strategies to harness their activity for the development of next-generation cancer immunotherapies.

    • Declan Pang
    • Alice Bertocchi
    • Mathilde Pohin
    Reviews
    Nature Reviews Immunology
    P: 1-15

  • Abnormalities in gut bacteria can contribute to hard-to-treat illnesses, such as inflammatory bowel diseases. Efforts to harness bacterium-targeting viruses reveal a promising way to tackle these conditions.

    • Alice Bertocchi
    • Fiona Powrie
    News & Views
    Nature
    Volume: 612, P: 220-221

  • Studies in mice show that effector T regulatory cells in the gut are most functional in the lamina propria, but this homeostatic niche is disrupted in inflammation, suggesting a spatial mechanism of tolerance to commensal microorganisms.

    • Yisu Gu
    • Raquel Bartolomé-Casado
    • Fiona Powrie
    ResearchOpen Access
    Nature
    Volume: 628, P: 854-862