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Advanced filters: Author: Alice Shasha Cheng Clear advanced filters

  • ADPKD is a genetic kidney disease caused by mutations in PKD1. Here, the authors develop broadly expressed and kidney specific promoter mediated adenine base editors to correct point mutation of Pkd1 gene, rescuing pathology in a humanized mouse model.

    • Alice Shasha Cheng
    • Linda Xiaoyan Li
    • Xiaogang Li
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15