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Showing 1–2 of 2 results
Advanced filters: Author: Allen Sam Titus Clear advanced filters

  • Nakada, Titus et al. show that p22phox, a heterodimeric partner of NADPH oxidases, prevents sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2a (SERCA2a) oxidation at Cys498 and its downregulation. This study suggests that therapeutic interventions to protect this residue may sustain SERCA2a expression in heart failure.

    • Yasuki Nakada
    • Allen Sam Titus
    • Junichi Sadoshima
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 4, P: 1187-1205

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103