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Showing 1–2 of 2 results
Advanced filters: Author: Anaïs Perrichet Clear advanced filters

  • Interleukin (IL)-1β has been shown to promote tumour growth in non-small cell lung cancer (NSCLC). Here the authors show using chemo-immunotherapy resistant mouse tumour models that IL-1β improves CD8 T cell recruitment in a CXCL10-dependent manner and IL-1β therapy could be a useful adjunct to chemotherapy and anti-PD-1.

    • Anaïs Perrichet
    • Julie Lecuelle
    • Cédric Rébé
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18

  • The function of type 3 innate lymphoid cells (ILC3s) in cancer is still poorly understood. Bruchard et al. demonstrate that ILC3s are critical for the recruitment of T cells to the tumor microenvironment and thereby play important roles in antitumor responses.

    • Mélanie Bruchard
    • Mannon Geindreau
    • François Ghiringhelli
    Research
    Nature Immunology
    Volume: 23, P: 262-274