Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Ana Jaklenec Clear advanced filters

  • mRNA vaccines combine rapid design, scalable manufacturing and strong safety profiles with applications across infectious diseases, cancer and autoimmune disorders. However, global access to mRNA vaccines remains limited. This Review explores how achieving equitable access depends on overcoming technical, logistical, economic and regulatory barriers through innovations in thermostability, delivery systems, alternative RNA platforms, artificial intelligence-driven design and optimization, and coordinated policy strategies.

    • Behnaz Eshaghi
    • Robert Langer
    • Ana Jaklenec
    Reviews
    Nature Reviews Bioengineering
    P: 1-22

  • This study reports the preparation of degradable poly(β-amino ester) microparticles as a promising replacement for nondegradable microplastics in cleansing products and food fortification, demonstrating effective cleansing, toxic element removal and robust nutrient protection with efficient release.

    • Linzixuan Zhang
    • Ruiqing Xiao
    • Ana Jaklenec
    ResearchOpen Access
    Nature Chemical Engineering
    Volume: 2, P: 77-89

  • Intradermal microneedles for the co-delivery of mRNA and near-infrared fluorescent microparticles are used in combination with deep learning-based image analysis for the simultaneous administration of therapeutics and registry of patient information records into the skin.

    • Jooli Han
    • Maria Kanelli
    • Ana Jaklenec
    ResearchOpen Access
    Nature Materials
    Volume: 24, P: 794-803

  • Mucosal vaccines are critical in the fight against mucosal pathogens because they enable the immune system to directly neutralize these pathogens at their primary site of entry. This Review examines the role of material design in addressing the challenges associated with mucosal vaccine delivery.

    • Behnaz Eshaghi
    • Alex Schudel
    • Ana Jaklenec
    Reviews
    Nature Reviews Materials
    Volume: 9, P: 29-45

  • CRISPR–Cas9 technology is a powerful tool for immune cell engineering. Ex vivo editing has progressed to clinical trials, but in vivo applications are still limited owing to delivery challenges. This Review summarizes these challenges as well as strategies and progress in delivering CRISPR–Cas9 to immune and non-immune cells.

    • Shahad K. Alsaiari
    • Behnaz Eshaghi
    • Ana Jaklenec
    Reviews
    Nature Reviews Materials
    Volume: 10, P: 44-61