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Advanced filters: Author: Anastasia M. Jacko Clear advanced filters

An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants

An oligodendrocyte-specific genomic silencer element determines the cell type specificity for a fatal neurological disorder caused by a widely expressed nuclear protein (Lamin B1) and suggests a role for silencer elements in disease causation.

Bruce Nmezi
Guillermo Rodriguez Bey
Quasar S. Padiath
ResearchOpen Access05 Feb 2025
Nature Communications

Volume: 16, P: 1-21
The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β

Jiaxing Miao
Lian Li
Jing Zhao
ResearchOpen Access02 Feb 2024
Experimental & Molecular Medicine

Volume: 56, P: 395-407
Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis

Ling Nan
Anastasia M. Jacko
Yutong Zhao
ResearchOpen Access08 Sept 2016
Scientific Reports

Volume: 6, P: 1-11