Microglia colonize germinal regions of the developing cerebral cortex and contribute to the regulation of neurogenesis but the mechanisms that regulate this are not clear. Here the authors show that brain progenitor cells, through the secretion of the chemokine Cxcl12, drive microglia to cluster into the germinal regions of the developing mouse cerebral cortex.
- Benedetta Arnò
- Francesca Grassivaro
- Luca Muzio
