The assembly of late-transition metal N-heterocyclic carbene (NHC) complexes often relies on costly and strong bases, limiting their practical synthesis. Here, the authors utilize gaseous and aqueous ammonia as weak bases in a continuous-flow system, achieving efficient synthesis of Au, Pd, and Cu-NHC complexes under milder and more concentrated conditions.
- Riku Saito
- Andreas Simoens
- Steven P. Nolan
