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Showing 101–150 of 190 results

Advanced filters: Author: Angelo Pan Clear advanced filters

Inhibition of Monocyte Chemotactic Protein-1 Synthesis by Statins

Maria Romano
Luisa Diomede
Alberto Mantovani
Research01 Jul 2000
Laboratory Investigation

Volume: 80, P: 1095-1100
The N-terminal 1-16 peptide derived in vivo from protein seminal vesicle protein IV modulates α-thrombin activity: potential clinical implications

Marilena Lepretti
Susan Costantini
Paola Stiuso
ResearchOpen Access31 Oct 2008
Experimental & Molecular Medicine

Volume: 40, P: 541-549
Circulating tumour DNA in early stage and locally advanced NSCLC: ready for clinical implementation?

Analysis of circulating tumour DNA (ctDNA) is commonly used for molecular profiling in patients with advanced-stage non-small-cell lung cancer (NSCLC). The authors of this Review summarize the available evidence on the potential utility of incorporating ctDNA in the management of those with early stage and locally advanced NSCLC and propose interventional studies to provide the necessary additional evidence.

Nicola Normanno
Alessandro Morabito
Antonella De Luca
Reviews20 Jan 2025
Nature Reviews Clinical Oncology

Volume: 22, P: 215-231
Cyclin E1 and Rb modulation as common events at time of resistance to palbociclib in hormone receptor-positive breast cancer

Cristina Guarducci
Martina Bonechi
Ilenia Migliaccio
ResearchOpen Access28 Nov 2018
npj Breast Cancer

Volume: 4, P: 1-10
Involvement of hyaluronan in the adaptive changes of the rat small intestine neuromuscular function after ischemia/reperfusion injury

Michela Bistoletti
Annalisa Bosi
Cristina Giaroni
ResearchOpen Access13 Jul 2020
Scientific Reports

Volume: 10, P: 1-17
HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy

Riccardo Cristofani
Margherita Piccolella
Roberta Manuela Moretti
ResearchOpen Access18 Nov 2022
Cell Death & Disease

Volume: 13, P: 1-15
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Interactomic exploration of LRRC8A in volume-regulated anion channels

Veronica Carpanese
Margherita Festa
Vanessa Checchetto
ResearchOpen Access22 Jun 2024
Cell Death Discovery

Volume: 10, P: 1-28
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

Yiqun Zhang
Fengju Chen
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice.

Joana Carlevaro-Fita
Andrés Lanzós
Christian von Mering
ResearchOpen Access05 Feb 2020
Communications Biology

Volume: 3, P: 1-16
Smart foliar fertilizer based on Zn-Alg-CaCO₃ microparticles improves Aquaponic tomato cultivation

Davide Frassine
Roberto Braglia
Antonella Canini
ResearchOpen Access24 May 2025
Scientific Reports

Volume: 15, P: 1-12
Author Correction: Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Kadir C. Akdemir
Victoria T. Le
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1079
Author Correction: Butler enables rapid cloud-based analysis of thousands of human genomes

Sergei Yakneen
Sebastian M. Waszak
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Biotechnology

Volume: 41, P: 577
Author Correction: The landscape of viral associations in human cancers

Marc Zapatka
Ivan Borozan
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1077
Author Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers

Yuan Yuan
Young Seok Ju
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1078
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Isidro Cortés-Ciriano
Jake June-Koo Lee
Christian von Mering
Amendments and CorrectionsOpen Access21 Mar 2023
Nature Genetics

Volume: 55, P: 1076
Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca²⁺ homeostasis, and severe muscle atrophy

Irene Pertici
Donato D’Angelo
Anna Raffaello
ResearchOpen Access14 Feb 2025
Cell Death & Disease

Volume: 16, P: 1-13
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

Yulia Rubanova
Ruian Shi
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Shimin Shuai
Federico Abascal
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Divergent mutational processes distinguish hypoxic and normoxic tumours

Vinayak Bhandari
Constance H. Li
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes

Matthew A. Reyna
David Haan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: The repertoire of mutational signatures in human cancer

Ludmil B. Alexandrov
Jaegil Kim
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E41
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer

Lina Sieverling
Chen Hong
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska
Jonathan Barenboim
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: Inferring structural variant cancer cell fraction

Marek Cmero
Ke Yuan
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Author Correction: The evolutionary history of 2,658 cancers

Moritz Gerstung
Clemency Jolly
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E42
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E40
Author Correction: Patterns of somatic structural variation in human cancer genomes

Yilong Li
Nicola D. Roberts
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E38
Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Wei Jiao
Gurnit Atwal
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
IMMUNOREACT 9 metachronous rectal cancers have high HLA-ABC expression on healthy epithelium but a lower infiltration of CD3+ T cells than primary lesions

Beatrice Salmaso
Melania Scarpa
Marco Scarpa
ResearchOpen Access30 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Mutations in all three genes encoding ribonuclease H2 sensitize cells to poly(ADP–ribose) polymerase inhibitors by compromising ribonucleotide excision repair.

Michal Zimmermann
Olga Murina
Daniel Durocher
Research04 Jul 2018
Nature

Volume: 559, P: 285-289
A gravitational-wave standard siren measurement of the Hubble constant

The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

B. P. Abbott
R. Abbott
M. Serra-Ricart
Research16 Oct 2017
Nature

Volume: 551, P: 85-88
Périgord black truffle genome uncovers evolutionary origins and mechanisms of symbiosis

The genome of the black truffle - one of the most popular truffles on the market - has been sequenced. This is the first genome of a symbiotic ascomycete to be analysed. Comparison with the genome of another ectomycorrhizal symbiotic fungus indicates that a genetic predisposition to symbiosis evolved differently in ascomycetes and basidiomycetes. The study also offers insight into fungal sex and fruiting.

Francis Martin
Annegret Kohler
Patrick Wincker
ResearchOpen Access28 Mar 2010
Nature

Volume: 464, P: 1033-1038
A single donor is sufficient to produce a highly functional in vitro antibody library

Here, the authors construct and validate an in vitro antibody library from a single, healthy donor. They demonstrate the functionality of the library using several therapeutically relevant targets and were able to obtain many different antibodies with the desired biophysical properties.

M. Frank Erasmus
Sara D’Angelo
Andrew R. M. Bradbury
ResearchOpen Access19 Mar 2021
Communications Biology

Volume: 4, P: 1-16
Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs

Carlo Brighi
Federico Salaris
Silvia Di Angelantonio
ResearchOpen Access15 May 2021
Cell Death & Disease

Volume: 12, P: 1-22
Modelling physiology of haemodynamic adaptation in short-term microgravity exposure and orthostatic stress on Earth

Parvin Mohammadyari
Giacomo Gadda
Angelo Taibi
ResearchOpen Access25 Feb 2021
Scientific Reports

Volume: 11, P: 1-13
Complex migration history is revealed by genetic diversity of tomato samples collected in Italy during the eighteenth and nineteenth centuries

M. R. Ercolano
A. Di Donato
L. Frusciante
ResearchOpen Access01 Jul 2020
Horticulture Research

Volume: 7, P: 1-8
The power of imaging to understand extracellular vesicle biology in vivo

This Review describes the state of the art in imaging extracellular vesicles in animals to study their release, biodistribution and uptake, and covers labeling strategies, microscopy methods and discoveries made in model organisms.

Frederik J. Verweij
Leonora Balaj
Guillaume van Niel
Reviews26 Aug 2021
Nature Methods

Volume: 18, P: 1013-1026
Rapid detection of AAV8 binding antibodies in gene therapy candidates: development of a point-of-care approach

Alexander Kozikowski
Qing Wang
Angelo H. Gunasekera
Research21 Aug 2025
Gene Therapy

Volume: 32, P: 610-620
Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer

Alessio Amatu
Alessio Somaschini
Salvatore Siena
ResearchOpen Access03 Dec 2015
British Journal of Cancer

Volume: 113, P: 1730-1734
Clinical implications of PTEN loss in prostate cancer

Genomic aberrations of thePTENtumour suppressor are among the most common in prostate cancer. In this Review, the authors describe the roles of PTEN, consider how PTEN status could act as a potential prognostic and predictive biomarker, and discuss the potential of PTEN and its downstream pathways as a therapeutic target.

Tamara Jamaspishvili
David M. Berman
Tamara L. Lotan
Reviews20 Feb 2018
Nature Reviews Urology

Volume: 15, P: 222-234
Epidemiology and genetic diversity of Streptococcus suis in smallhold swine farms in the Philippines

Susan A. Sedano
Mary Grace Concepcion T. Cantalejo
Benji Brayan Ilagan Silva
ResearchOpen Access01 Dec 2023
Scientific Reports

Volume: 13, P: 1-12
Biofortified tomatoes provide a new route to vitamin D sufficiency

Vitamin D insufficiency is a major public health problem requiring dietary fortification and supplement solutions. This study produced gene-edited tomato lines that accumulate provitamin D₃ in fruits, offering a new dietary source of vitamin D₃.

Jie Li
Aurelia Scarano
Cathie Martin
ResearchOpen Access23 May 2022
Nature Plants

Volume: 8, P: 611-616
Moonlighting transcriptional activation function of a fungal sulfur metabolism enzyme

Elisabetta Levati
Sara Sartini
Barbara Montanini
ResearchOpen Access28 Apr 2016
Scientific Reports

Volume: 6, P: 1-11
Establishment and characterization of a novel cell line derived from human thymoma AB tumor

Yesim Gökmen-Polar
Kerry L Sanders
George W Sledge Jr
Research27 Aug 2012
Laboratory Investigation

Volume: 92, P: 1564-1573
Differentiating erythroblasts adapt to mechanical stimulation by upregulation of cholesterol biosynthesis via S1P/SREBP-induced HMGCR expression

Giulia Iacono
Asena Abay
Emile van den Akker
ResearchOpen Access04 Dec 2024
Scientific Reports

Volume: 14, P: 1-15
RSK1 dependency in FLT3-ITD acute myeloid leukemia

Tim Kong
Angelo B. A. Laranjeira
Stephen T. Oh
ResearchOpen Access26 Nov 2024
Blood Cancer Journal

Volume: 14, P: 1-10
Challenges in the management of advanced, ER-positive, HER2-negative breast cancer

Hormone-receptor-positive breast cancer accounts for the majority of all breast cancers. The evolution of this disease from early stage to the metastatic setting leads to increased heterogeneity and the development of treatment resistance representing a great challenge for management decisions. In this Review, we examine the current evidence that can guide treatment decisions in patients with advanced-stage ER+ breast cancer, discuss how to tackle these therapeutic challenges and provide suggestions for the optimal management of this patient population.

Christopher D. Hart
Ilenia Migliaccio
Angelo Di Leo
Reviews26 May 2015
Nature Reviews Clinical Oncology

Volume: 12, P: 541-552
Characterization of sinoatrial automaticity in Microcebus murinus to study the effect of aging on cardiac activity and the correlation with longevity

Mattia L. DiFrancesco
Manon Marrot
Angelo G. Torrente
ResearchOpen Access21 Feb 2023
Scientific Reports

Volume: 13, P: 1-16

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