Nature Search

Polygenic risk score and cluster-based analysis suggests links between type 2 diabetes and vascular dementia in the KARE study

Type 2 diabetes is an established risk factor for dementia. Here, the authors use data from 33,136 older Chinese adults to show that polygenic risk for type 2 diabetes was associated with vascular dementia but not Alzheimer’s disease.

Wanqing Dong
Zijian Tian
Hongwei Jiang
ResearchOpen Access19 Nov 2025
Nature Communications

Volume: 16, P: 1-8
Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies

A gene therapy method using AAV can help deliver HIV-fighting antibodies long-term, but the body often rejects them. Here the authors show that a short course of the drug rapamycin helps prevent host anti-drug antibody responses, showing successful antibody delivery in mice and monkeys.

Sebastian P. Fuchs
Paula G. Mondragon
Ronald C. Desrosiers
ResearchOpen Access07 Oct 2025
Nature Communications

Volume: 16, P: 1-12
Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii

Here the authors show an intermediate state of the photosystem II (PSII) repair cycle, where three protein factors and an α-tocopherol quinone molecule are associated with a damaged PSII at distinct sites, fulfilling their specific functions in the repair process.

Anjie Li
Tingting You
Zhenfeng Liu
ResearchOpen Access18 Jun 2024
Nature Communications

Volume: 15, P: 1-17
Structural basis of LhcbM5-mediated state transitions in green algae

High-resolution structures of the PSI–LHCI–LHCII supercomplex from Chlamydomonas reinhardtii reveal the mechanism of assembly between the PSI–LHCI complex and two phosphorylated LHCII trimers.

Xiaowei Pan
Ryutaro Tokutsu
Mei Li
Research08 Jul 2021
Nature Plants

Volume: 7, P: 1119-1131
Vaping and oral surgery

Anjie Li
Research28 Jun 2024
BDJ Student

P: 1-2
Roles of multiple TEF30-associated intermediate complexes in the repair and reassembly of photosystem II in Chlamydomonas reinhardtii

Cryo-EM structures of four TEF30-associated photosystem II repair complexes from Chlamydomonas reinhardtii reveal versatile roles of TEF30 in the reassembly of the photosystem II core monomer, dimer and supercomplex through multiple intermediate states.

Yidi Wang
Chenxi Wang
Zhenfeng Liu
Research27 Jun 2025
Nature Plants

Volume: 11, P: 1455-1469
Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants

The researchers have uncovered that the phase separation ability of plant heterochromatin protein ADCP1 variants defines the formation of heterochromatic condensates (chromocenters) in different plant species.

Weifeng Zhang
Lingling Cheng
Qianwen Sun
Research16 Jul 2024
Nature Plants

Volume: 10, P: 1215-1230
A method for detecting metal surface defects using a dynamic fine-grained multi-branch encoder

Cheng Liu
Kai Chen
Nanchao Wang
ResearchOpen Access29 Dec 2025
Scientific Reports

Volume: 16, P: 1-18
Structural insight into light harvesting for photosystem II in green algae

High-resolution cryo-EM structures of Chlamydomonas light-harvesting complex II (LHCII)–photosystem II (PSII) supercomplexes show loosely and moderately associated LHCIIs forming multiple pathways for energy transfer to PSII reaction centres.

Xin Sheng
Akimasa Watanabe
Zhenfeng Liu
Research25 Nov 2019
Nature Plants

Volume: 5, P: 1320-1330
Architecture of chloroplast TOC–TIC translocon supercomplex

A cryo-electron microscopy analysis of the Chlamydomonas reinhardtii TOC–TIC supercomplex reveals that Tic214 traverses the chloroplast inner membrane, the intermembrane space and the outer membrane, connecting the TOC complex with the TIC proteins.

Hao Liu
Anjie Li
Zhenfeng Liu
Research26 Jan 2023
Nature

Volume: 615, P: 349-357
Correction: CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Qun Zhao
Jingyi Wu
Xianjun Yu
Amendments and CorrectionsOpen Access29 Jul 2025
Cell Death & Disease

Volume: 16, P: 1
Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1

The crystallographic and cryo-EM structures of CB1 bound to the positive allosteric modulator ZCZ011, combined with molecular dynamics simulations and mutagenesis experiments, reveal allosteric modulation of CB1 by rearrangement of the TM2 and TM3 transmembrane domains.

Xin Yang
Xuehui Wang
Shengyong Yang
Research30 May 2022
Nature Chemical Biology

Volume: 18, P: 831-840
Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer

Yankui Liu
Anjie Chen
Yuanyuan Mi
ResearchOpen Access05 Feb 2025
Cell Death & Disease

Volume: 16, P: 1-14
CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Qun Zhao
Jingyi Wu
Xianjun Yu
ResearchOpen Access05 May 2025
Cell Death & Disease

Volume: 16, P: 1-15
Current evidence on the relationships among five polymorphisms in the matrix metalloproteinases genes and prostate cancer risk

Jiandong Gui
Hangsheng Zhou
Yuanyuan Mi
ResearchOpen Access18 May 2024
Scientific Reports

Volume: 14, P: 1-9
A new generation M^pro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Chong Huang
Huiping Shuai
Shengyong Yang
ResearchOpen Access16 Mar 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-13
Childhood absence epilepsy and distinct dynamic functional network connectivity patterns in self-limited epilepsy with centrotemporal spikes: a resting-state fMRI study

Linfeng Song
Guangrong Wu
Lin Jiang
Research11 Oct 2025
Pediatric Research

P: 1-13
Microalgal-bacterial granular sludge can remove complex organics from municipal wastewater with algae-bacteria interactions

Complex organics in municipal wastewater can be removed through treatment with microalgal-bacterial granular sludge in day-night cycles, with an efficiency depending on the carbon-to-nitrogen ratio, suggest experiments with raw wastewater from two sites in China.

Yuting Shi
Chengxiang Xu
Yu Liu
ResearchOpen Access24 Jun 2024
Communications Earth & Environment

Volume: 5, P: 1-10

Search

Polygenic risk score and cluster-based analysis suggests links between type 2 diabetes and vascular dementia in the KARE study

Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies

Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii

Structural basis of LhcbM5-mediated state transitions in green algae

Vaping and oral surgery

Roles of multiple TEF30-associated intermediate complexes in the repair and reassembly of photosystem II in Chlamydomonas reinhardtii

Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants

A method for detecting metal surface defects using a dynamic fine-grained multi-branch encoder

Structural insight into light harvesting for photosystem II in green algae

Architecture of chloroplast TOC–TIC translocon supercomplex

Correction: CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1

Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer

CXCL13 suppresses liver regeneration through the negative regulation of HGF signaling

Current evidence on the relationships among five polymorphisms in the matrix metalloproteinases genes and prostate cancer risk

A new generation M^pro inhibitor with potent activity against SARS-CoV-2 Omicron variants

Childhood absence epilepsy and distinct dynamic functional network connectivity patterns in self-limited epilepsy with centrotemporal spikes: a resting-state fMRI study

Microalgal-bacterial granular sludge can remove complex organics from municipal wastewater with algae-bacteria interactions

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