Hereditary disease should be suspected in pheochromocytoma, even when the etiology is apparently sporadic. Mutations have been described inRET, VHL and NF1, as well as in the succinate dehydrogenase genes. The authors discuss the need for genetic screening in possible cases of familial pheochromocytoma and recommend which patients to screen and when.
- Pierre-François Plouin
- Anne-Paule Gimenez-Roqueplo
