In humans, pH varies across the gastrointestinal tract. This Review provides an overview of gastrointestinal pH and its role in shaping the gut microbiota, highlighting major physiological and dietary factors that influence gastrointestinal pH and how in turn pH affects microbiota composition and metabolism in health and, potentially, disease.
- Julius E. Brinck
- Anurag K. Sinha
- Tine R. Licht