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Showing 1–10 of 10 results
Advanced filters: Author: Arif A. Hamid Clear advanced filters
  • Seeking insight into dopamine's contribution to motivation and learning, the authors examined dopamine release in the rat nucleus accumbens during adaptive decision-making. Dopamine levels convey a running estimate of available future reward, which is used to decide whether it's worthwhile to engage in a behavioral task. Abrupt fluctuations serve as reward prediction errors, reinforcing behavioral choices.

    • Arif A Hamid
    • Jeffrey R Pettibone
    • Joshua D Berke
    Research
    Nature Neuroscience
    Volume: 19, P: 117-126
  • The dopamine projection from midbrain dopamine cells to the nucleus accumbens is essential for normal motivation, yet motivation-related changes in nucleus accumbens dopamine release occur independently of dopamine cell firing.

    • Ali Mohebi
    • Jeffrey R. Pettibone
    • Joshua D. Berke
    Research
    Nature
    Volume: 570, P: 65-70
  • Despite large sequencing and data sharing efforts it often remains challenging to provide a genetic diagnosis for individuals with suspected Mendelian (single-gene) disorders. Here, the authors describe their experiences in identifying likely causal genetic variants in thousands of families and highlight the need to consider a wide range of challenges rather than a narrow focus on sequencing technologies.

    • Lama AlAbdi
    • Sateesh Maddirevula
    • Fowzan S. Alkuraya
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19
  • Deep-space exploration missions require new technologies that can support astronaut health systems as well as biological monitoring and research systems that can function independently from Earth-based mission control centres. A NASA workshop explored how artificial intelligence advances could help address these challenges and, in this first of two Review articles based on the findings from the workshop, a vision for autonomous biomonitoring and precision space health is discussed.

    • Ryan T. Scott
    • Lauren M. Sanders
    • Sylvain V. Costes
    Reviews
    Nature Machine Intelligence
    Volume: 5, P: 196-207
  • Deep space exploration missions will require new technologies that can support astronaut health systems, as well as biological monitoring and research systems that can function independently from Earth-based mission control centres. A NASA workshop explored how artificial intelligence advances could help address these challenges and, in this second of two Review articles based on the findings from the workshop, the intersection between artificial intelligence and space biology is discussed.

    • Lauren M. Sanders
    • Ryan T. Scott
    • Sylvain V. Costes
    Reviews
    Nature Machine Intelligence
    Volume: 5, P: 208-219