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Advanced filters: Author: Arijita Ghosh Clear advanced filters

Capture at the ER-mitochondrial contacts licenses IP₃ receptors to stimulate local Ca²⁺ transfer and oxidative metabolism

The formation and dissolution of ER-Mitochondria contacts is unclear. Here, authors show that the IP3 receptor traffics in and out of the contacts and, when trapped, improves calcium signaling to stimulate energy metabolism.

Máté Katona
Ádám Bartók
György Hajnóczky
ResearchOpen Access09 Nov 2022
Nature Communications

Volume: 13, P: 1-11
The roles of mitochondria in global and local intracellular calcium signalling

Mitochondria rapidly take up calcium (Ca²⁺) from the cytoplasm and neighbouring organelles upon an increase in local and global calcium levels, thereby stimulating metabolism and regulating processes that are sensitive to Ca²⁺. This Review discusses mitochondrial calcium trafficking and its dysregulation in disease.

Benjamín Cartes-Saavedra
Arijita Ghosh
György Hajnóczky
Reviews27 Jan 2025
Nature Reviews Molecular Cell Biology

Volume: 26, P: 456-475
Functional characterization of thermotolerant microbial consortium for lignocellulolytic enzymes with central role of Firmicutes in rice straw depolymerization

Parmeshwar V. Gavande
Arijita Basak
Shilpi Ghosh
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-13

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