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Showing 1–14 of 14 results
Advanced filters: Author: Arnau Sebé-Pedrós Clear advanced filters

  • This study reconstructs the gene regulatory networks that define cell types in the sea anemone Nematostella vectensis, providing a valuable resource for comparative regulatory genomics and the evolution of new cell types.

    • Anamaria Elek
    • Marta Iglesias
    • Arnau Sebé-Pedrós
    Research
    Nature Ecology & Evolution
    Volume: 10, P: 140-153

  • Recent phylogenetic analyses have identified orphan clades, including Xenacoelomorphs, that can offer insights into bilaterian evolution. Here they generate a cell type atlas of Xenoturbella bockithat highlights cellular diversity in the nervous system and other tissues, reinforcing the idea of parallel evolution of cell types across animals.

    • Helen E. Robertson
    • Arnau Sebé-Pedrós
    • Heather Marlow
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Genomic sequencing of the thermotolerant coral species Oculina patagonica, single-cell transcriptomic analyses of symbiotic and non-symbiotic specimens and comparisons with obligate symbiotic coral species reveal adaptations that provide resilience to coral bleaching.

    • Shani Levy
    • Xavier Grau-Bové
    • Arnau Sebé-Pedrós
    Research
    Nature
    Volume: 648, P: 368-376

  • The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.

    • Iana V. Kim
    • Cristina Navarrete
    • Arnau Sebé-Pedrós
    ResearchOpen Access
    Nature
    Volume: 642, P: 1097-1105

  • The evolution of the vertebrate head mesoderm involved the emergence of new structures and cell types. Here the authors generated a cell atlas of the cephalochordate neurula to study the origins of these novelties and propose a revised scenario for the evolution of the vertebrate head muscles.

    • Xavier Grau-Bové
    • Lucie Subirana
    • Hector Escriva
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Comparative genomics and proteomics of archaea and eukaryotes are used to explore the evolutionary history of eukaryotic chromatin, including modifications, catalytic functions and relationship with genomic parasites.

    • Xavier Grau-Bové
    • Cristina Navarrete
    • Arnau Sebé-Pedrós
    Research
    Nature Ecology & Evolution
    Volume: 6, P: 1007-1023

  • Guifré Torruella et al. present the first transcriptome data of an aphelid species, which multi-gene phylogenomic analyses place as the closest relative of fungi. They are able to infer a free-living-like aphelid proteome and suggest that fungi evolved through the loss of phagotrophy from aphelid-like ancestors.

    • Guifré Torruella
    • Xavier Grau-Bové
    • Purificación López-García
    ResearchOpen Access
    Communications Biology
    Volume: 1, P: 1-11

  • The Biodiversity Cell Atlas aims to create comprehensive single-cell molecular atlases across the eukaryotic tree of life, which will be phylogenetically informed, rely on high-quality genomes and use shared standards to facilitate comparisons across species.

    • Arnau Sebé-Pedrós
    • Amos Tanay
    • Bo Wang
    Reviews
    Nature
    Volume: 645, P: 877-885

  • Multicellular organisms rely on a complex interplay between diverse cell types, but how multicellularity evolved from unicellular ancestors has long been a debated research question. In this Review, the authors describe how comparative and functional genomics have provided valuable insights into the transition between unicellularity and multicellularity, including how various molecular networks have been adopted for multicellular life.

    • Arnau Sebé-Pedrós
    • Bernard M. Degnan
    • Iñaki Ruiz-Trillo
    Reviews
    Nature Reviews Genetics
    Volume: 18, P: 498-512

  • Unicellular ancestors of metazoans can provide significant insights into the origin of multicellularity. Suga et al. present the first complete genome of the filasterean Capsaspora owczarzakiand suggest an evolutionary mechanism for the transition from unicellular protists to metazoans.

    • Hiroshi Suga
    • Zehua Chen
    • Iñaki Ruiz-Trillo
    ResearchOpen Access
    Nature Communications
    Volume: 4, P: 1-9