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Showing 1–5 of 5 results
Advanced filters: Author: Aryan Taheri Clear advanced filters

  • NuMA activates dynein to organize the mitotic spindle by linking motor-driven transport with microtubule (MT) minus-end control. Mitotic phosphorylation relieves NuMA autoinhibition, enabling dynein motility and focusing MT minus-ends into asters.

    • Merve Aslan
    • Ennio A. d’Amico
    • Ahmet Yildiz
    Research
    Nature Chemical Biology
    P: 1-12

  • Plant Augmin cryo-EM structures reveal a 40-nm hetero-octameric fork with coiled-coil interfaces, dual CH domains at V-junction switch for microtubule binding and NEDD1 β-propeller binding to the V-junction boosts anti-parallel Augmin dimerization, recruiting γ-TuRC for branch nucleation.

    • Md Ashaduzzaman
    • Aryan Taheri
    • Jawdat Al-Bassam
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20