Extracellular contractile injection systems (eCISs) are bacteriophage tail-derived toxin delivery complexes that are present in many prokaryotes. Here, the authors present an analysis of eCIS tail fiber genes in bacterial and archaeal genomes, providing insights into their diversity, target cells, functional adaptations, and evolutionary dynamics.
- Nimrod Nachmias
- Zhiren Wang
- Asaf Levy
