Nature Search

Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients

Asako Nakamura
Shinya Matsuura
K. Komatsu
Research01 Jan 1999
Journal of Human Genetics

Volume: 44, P: 48-51
Japan turns to functional genomics

Asako Saegusa
Research01 Jun 1999
Nature Biotechnology

Volume: 17, P: 527-528
GM food regulatory terms debated

Asako Saegusa
Research01 May 2000
Nature Biotechnology

Volume: 18, P: 484-485
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Japan pushes to capitalize on biotechnology

Asako Saegusa
Research01 Apr 1999
Nature Biotechnology

Volume: 17, P: 320-321
Japan renews gene therapy efforts...

Asako Saegusa
News01 Nov 1998
Nature Medicine

Volume: 4, P: 1213
Economy lifeline viewed as mixed blessing

tokyo
Japan's largest-ever economic stimulus package is being viewed with mixed reactions by the scientific community.

Asako Saegusa
News07 May 1998
Nature

Volume: 393, P: 5
Japan patent directives

Asako Saegusa
News01 Dec 1999
Nature Biotechnology

Volume: 17, P: 1148
Deciphering the inhibitory effects of trimetazidine on pulmonary hypertension development via decreasing fatty acid oxidation and promoting glucose oxidation

Asako Yanagisawa
Jun-Dal Kim
Koichiro Tatsumi
ResearchOpen Access07 Nov 2024
Scientific Reports

Volume: 14, P: 1-15
Complete sequencing and characterization of 21,243 full-length human cDNAs

Toshio Ota
Yutaka Suzuki
Sumio Sugano
Research21 Dec 2003
Nature Genetics

Volume: 36, P: 40-45
Holographic hyperbranched polymer nanocomposite grating with exceptionally large neutron scattering length density modulation amplitudes

Elhoucine Hadden
Jürgen Klepp
Yasuo Tomita
ResearchOpen Access26 Aug 2025
Scientific Reports

Volume: 15, P: 1-7
A genome-wide association study identifies the GPM6A locus associated with age at onset in ALS

A genome-wide association study in Japanese patients with ALS identifies rs113161727 at the ADAM29-GPM6A locus as a modifier of age at onset and links it to GPM6A upregulation.

Ryoichi Nakamura
Genki Tohnai
Gen Sobue
ResearchOpen Access05 Dec 2025
Communications Biology

Volume: 8, P: 1-11
Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s

Weng Sheng Kong
Naohiro Tsuyama
Masamoto Kanno
ResearchOpen Access23 Jun 2021
Scientific Reports

Volume: 11, P: 1-22
Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen

The hepatitis B vaccine is recognised as the most effective approach in reducing hepatitis-B-related morbidity; vaccine-escape mutations are however capable of infecting vaccinated individuals. In this work, authors aim to establish a hepatitis B vaccine candidate, which they assess in rhesus macaques in terms of efficacy and safety.

Ayaka Washizaki
Asako Murayama
Takanobu Kato
ResearchOpen Access05 Sept 2022
Nature Communications

Volume: 13, P: 1-12
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Tokyo's plan for new campus under threat

tokyo
An ambitious plan by Tokyo University to build a new campus 20 miles from the centre of Tokyo, is hanging in the balance over difficulties in raising the funds needed to purchase the land.

Asako Saegusa
News02 Apr 1998
Nature

Volume: 392, P: 429
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mammalian genomes are scattered with repetitive sequences, but their biology remains largely elusive. Here, the authors show that transcription can initiate from short tandem repetitive sequences, and that genetic variants linked to human diseases are preferentially found at repeats with high transcription initiation level.

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
ResearchOpen Access02 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Genome sequence and analysis of the Japanese morning glory Ipomoea nil

Japanese morning glory (Ipomoea nil) has diverse flowering traits. Here, the authors describe the reference genome sequence of I. nil, annotations of genes and transposons, and compare evolution of the I. nilgenome to other Convolvulaceae and Solanales genomes.

Atsushi Hoshino
Vasanthan Jayakumar
Yasubumi Sakakibara
ResearchOpen Access08 Nov 2016
Nature Communications

Volume: 7, P: 1-10
Gut environment-induced intraepithelial autoreactive CD4⁺ T cells suppress central nervous system autoimmunity via LAG-3

Experimental autoimmune encephalomyelitis (EAE) involves inflammatory cell infiltration into the central nervous system (CNS) and models the human disease multiple sclerosis. Here the authors show that transferred CD4+ gut intraepithelial lymphocytes can migrate into the CNS and inhibit inflammation in recipient mice with EAE.

Atsushi Kadowaki
Sachiko Miyake
Takashi Yamamura
ResearchOpen Access20 May 2016
Nature Communications

Volume: 7, P: 1-16
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis

Daijiro Konno
Go Shioi
Fumio Matsuzaki
Research16 Dec 2007
Nature Cell Biology

Volume: 10, P: 93-101
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

In vitro studies in human cell lines and in vivo studies in a hamster model show that the SARS-CoV-2 Omicron variant is less pathogenic than both the Delta variant and an ancestral strain of SARS-CoV-2.

Rigel Suzuki
Daichi Yamasoba
Kei Sato
ResearchOpen Access01 Feb 2022
Nature

Volume: 603, P: 700-705
The N⁶-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity

In this work, Yoshinaga et al. use functional CRISPR screens and in vivo analyses to show that an RNA methyltransferase METTL16 and MTR4-nuclear exosome play an essential role in maintaining erythropoiesis and regulating DNA repair in erythroblasts.

Masanori Yoshinaga
Kyuho Han
Osamu Takeuchi
ResearchOpen Access28 Oct 2022
Nature Communications

Volume: 13, P: 1-17
Preparation of photo-responsive hybrid materials based on hydrogels involving imidazolium-presenting gold nanoparticles

Homogeneously dispersed states of the modified gold nanoparticles were obtained in the hydrogel with the interaction of the imidazolium units tethered to both the nanoparticle surfaces and the side chains of the networks. Initially, by swelling and shrinking the hydrogels, it was found that the absorption properties can be changed. Next, by using the photo-responsive mono-carboxylate linker, we observed the photo-triggered modulation of the absorption properties of the hydrogels. These results can be explained by the change of the interparticle distances of the nanoparticles in the hydrogel matrices.

Kazuo Tanaka
Kensuke Naka
Yoshiki Chujo
Research07 Oct 2015
Polymer Journal

Volume: 48, P: 177-181
Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects

Takashi Kobayashi
Takaomi Kessoku
Atsushi Nakajima
ResearchOpen Access25 Jan 2025
Scientific Reports

Volume: 15, P: 1-11
Early CD4⁺ T cell responses induced by the BNT162b2 SARS-CoV-2 mRNA vaccine predict immunological memory

Jie Bai
Asako Chiba
Sachiko Miyake
ResearchOpen Access27 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
COVID-19 risk perceptions in Japan: a cross-sectional study

Asako Chiba
Taisuke Nakata
Reo Takaku
ResearchOpen Access23 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Mathys Grapotte
Manu Saraswat
Charles-Henri Lecellier
Amendments and CorrectionsOpen Access01 Mar 2022
Nature Communications

Volume: 13, P: 1
Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients

Hisayo Matsuyama
Takuma Isshiki
Sachiko Miyake
ResearchOpen Access12 Sept 2019
Scientific Reports

Volume: 9, P: 1-9
Diagnostic comparison of vibration-controlled transient elastography and MRI techniques in overweight and obese patients with NAFLD

Asako Nogami
Masato Yoneda
Atsushi Nakajima
ResearchOpen Access19 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Identification and genetic diversity analysis of a male-sterile gene (MS1) in Japanese cedar (Cryptomeria japonica D. Don)

Yoichi Hasegawa
Saneyoshi Ueno
Yoshinari Moriguchi
ResearchOpen Access15 Jan 2021
Scientific Reports

Volume: 11, P: 1-9
Maternal clinic and home blood pressure measurements during pregnancy and infant birth weight: the BOSHI study

Noriyuki Iwama
Hirohito Metoki
Naho Sato
Research29 Oct 2015
Hypertension Research

Volume: 39, P: 151-157

Search

Four novel mutations of the Fanconi anemia group A gene (FAA) in Japanese patients

Japan turns to functional genomics

GM food regulatory terms debated

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Japan pushes to capitalize on biotechnology

Japan renews gene therapy efforts...

Economy lifeline viewed as mixed blessing

Japan patent directives

Deciphering the inhibitory effects of trimetazidine on pulmonary hypertension development via decreasing fatty acid oxidation and promoting glucose oxidation

Complete sequencing and characterization of 21,243 full-length human cDNAs

Holographic hyperbranched polymer nanocomposite grating with exceptionally large neutron scattering length density modulation amplitudes

A genome-wide association study identifies the GPM6A locus associated with age at onset in ALS

Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s

Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Tokyo's plan for new campus under threat

Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Genome sequence and analysis of the Japanese morning glory Ipomoea nil

Gut environment-induced intraepithelial autoreactive CD4⁺ T cells suppress central nervous system autoimmunity via LAG-3

Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

The N⁶-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity

Preparation of photo-responsive hybrid materials based on hydrogels involving imidazolium-presenting gold nanoparticles

Lactiplantibacillus plantarum 22 A-3 ameliorates leaky gut in mice through its anti-inflammatory effects

Early CD4⁺ T cell responses induced by the BNT162b2 SARS-CoV-2 mRNA vaccine predict immunological memory

COVID-19 risk perceptions in Japan: a cross-sectional study

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients

Diagnostic comparison of vibration-controlled transient elastography and MRI techniques in overweight and obese patients with NAFLD

Identification and genetic diversity analysis of a male-sterile gene (MS1) in Japanese cedar (Cryptomeria japonica D. Don)

Maternal clinic and home blood pressure measurements during pregnancy and infant birth weight: the BOSHI study

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