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Showing 1–2 of 2 results
Advanced filters: Author: Aurélie Barrail-Tran Clear advanced filters

  • Mchantaf et al. explore HIV-1 persistence in five anatomical compartments in people living with HIV on successful Dolutegravir therapy. They find the highest levels of infection and viral transcription in lymph nodes, and that persistence is not associated with the selection of drug resistance mutations to Dolutegravir.

    • Gilbert Mchantaf
    • Adeline Melard
    • Véronique Avettand-Fenoel
    ResearchOpen Access
    Communications Medicine
    P: 1-10

  • HIV remission has been seen in people living with HIV after the cessation of antiretroviral therapy and is termed post treatment control. Here Passaes and colleagues present an SIV model that shows early initiation of antiretroviral therapy after SIV infection is linked to improved post treatment control upon cessation of antiviral therapy and associates with the expansion of an enhanced memory pool of CD8 + T cells‘.

    • Caroline Passaes
    • Delphine Desjardins
    • Asier Sáez-Cirión
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19