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Showing 1–8 of 8 results
Advanced filters: Author: Aurelie Di Cicco Clear advanced filters

  • ESCRT-III complexes assemble in vivo inside membrane structures with a negative Gaussian curvature, but how membrane shape influences ESCRT-III polymerization remains unclear. Here authors use structural and biophysical methods to show how human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation.

    • Aurélie Bertin
    • Nicola de Franceschi
    • Patricia Bassereau
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Septins are cytoskeletal filaments that localize at constriction sites and impact membrane remodeling. Here authors examine the curvature sensitivity of septins using bilayers on wavy patterns and derive a theoretical model that quantitatively describe the results.

    • Alexandre Beber
    • Cyntia Taveneau
    • Aurélie Bertin
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • Canon et al. offer insights into the auto-inhibition and activation of the minus-end directed motor myosin VI. The work highlights how differential relief of auto-inhibition allows for fine control of myosin VI activity in vivo.

    • Louise Canon
    • Carlos Kikuti
    • Anne Houdusse
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • The same type of polymer network deforms cell membranes inward, to absorb external material, and outward, to facilitate signal transmission. Experiments and theory show that these deformations are regulated by membrane tension and network mesh size.

    • Camille Simon
    • Rémy Kusters
    • Cécile Sykes
    Research
    Nature Physics
    Volume: 15, P: 602-609

  • The non-processive motor protein myosin 1b is required for Golgi membrane tubulation. Using a minimal reconstituted system and theoretical analysis, Yamada et al.demonstrate that the mechanism of tubule extraction depends on the catch bond properties of myosin 1b.

    • Ayako Yamada
    • Alexandre Mamane
    • Patricia Bassereau
    Research
    Nature Communications
    Volume: 5, P: 1-8

  • Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Here authors designed an in vitro MCS suitable for cryotomography and sub-tomogram analysis which sheds light on the recruitment of proteins of different sizes within MCS of adjustable thickness.

    • Eugenio de la Mora
    • Manuela Dezi
    • Daniel Lévy
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14