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Showing 1–7 of 7 results
Advanced filters: Author: Avishay Spitzer Clear advanced filters

  • Integrated single-cell transcriptomic and genetic characterization of 121 adult glioblastomas identifies heterogeneity at cell type, cell state and baseline expression program levels associated with specific mutations that form three stereotypical ecosystems.

    • Masashi Nomura
    • Avishay Spitzer
    • Itay Tirosh
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 1155-1167

  • In glioma, malignant synapses hijack mechanisms of synaptic plasticity to increase glutamate-dependent currents in tumour cells and the formation of neuron–glioma synapses, thereby promoting tumour proliferation and progression.

    • Kathryn R. Taylor
    • Tara Barron
    • Michelle Monje
    ResearchOpen Access
    Nature
    Volume: 623, P: 366-374

  • A type Ia supernova shows the presence of helium-rich circumstellar material, as demonstrated by its spectral features, infrared emission and a radio counterpart, that probably originates from a single-degenerate system in which a white dwarf accretes material from a helium donor star.

    • Erik C. Kool
    • Joel Johansson
    • Daniel Stern
    ResearchOpen Access
    Nature
    Volume: 617, P: 477-482

  • A study identifies 41 consensus gene expression meta-programs that are coordinately upregulated in subpopulations of malignant cells across tumour types, providing a comprehensive picture of hallmarks of intratumour heterogeneity.

    • Avishai Gavish
    • Michael Tyler
    • Itay Tirosh
    Research
    Nature
    Volume: 618, P: 598-606

  • Observations of declining ultraviolet emission from a type Ia supernova within four days of the explosion are as expected if material ejected by the supernova collided with a companion star, supporting the single degenerate channel model of supernova progenitors.

    • Yi Cao
    • S. R. Kulkarni
    • Neil Gehrels
    Research
    Nature
    Volume: 521, P: 328-331