Biological cofactors such as dihydronicotinamides are exploited by extant enzymes as hydride transfer agents and electron carriers but are generally inefficient to facilitate any reactions on their own. Here, the authors report short peptide-based amyloid nanotubes featuring exposed arrays of cationic and hydrophobic residues that can bind small hydride transfer agents (NaBH4) to facilitate efficient reduction of ester substrates in water.
- Ayan Chatterjee
- Surashree Goswami
- Dibyendu Das