Nature Search

Microbial activation of the GLP-2R mitigates gastrointestinal inflammation

Here, Yang-Jensen et al. demonstrate that a scalable microbial protein lysate from Methylococcus capsulatus Bath reshapes gut microbiota and T cells and, via fermentation-driven GLP-2 receptor mimicry, protects against gastrointestinal inflammation while providing sustainable protein nutrition

Sune K. Yang-Jensen
Béatrice S.-Y. Choi
Benjamin A. H. Jensen
ResearchOpen Access15 Jan 2026
Nature Communications

P: 1-16
Bunching of 8–10 keV auroral electrons near an artificial electron beam

M. P. Gough
B. N. Maehlum
G. Ventura
Research04 Sept 1980
Nature

Volume: 287, P: 15-17
Does U–Pb date Earth's core formation?; How well can Pb isotopes date core formation? (Reply)

B. J. Wood
A. N. Halliday
Research01 Nov 2006
Nature

Volume: 444, P: E2-E3
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

Hutchinson-Gilford Progeria Syndrome is characterized by premature aging with cardiovascular disease being the main cause of death. Here the authors show that inhibition of the NAT10 enzyme enhances cardiac function and fitness, and reduces age-related phenotypes in a mouse model of premature aging.

Gabriel Balmus
Delphine Larrieu
Stephen P. Jackson
ResearchOpen Access27 Apr 2018
Nature Communications

Volume: 9, P: 1-14
The impact of supramolecular self-association of organocatalysts on catalytic performance

Non-covalent interactions between organocatalyst molecules can change catalytic behaviour, leading to changes in reaction rates and selectivities. This Review discusses how to identify such interactions, measure their effect on catalysis and ultimately how to avoid or exploit them in synthesis.

Shounak Hinge
Sohom Kundu
Jochen Niemeyer
Reviews17 Sept 2025
Nature Reviews Chemistry

Volume: 9, P: 688-706
Molecular cloning and organization of two leghaemoglobin genomic sequences of soybean

D. Sullivan
N. Brisson
D. Y. Thomas
Research05 Feb 1981
Nature

Volume: 289, P: 516-518
Hiding behind the curtain: performance information and public officials’ policy instrument preferences in visible and invisible domains

Zengqiang Qin
Jinfeng Zhang
Bingsheng Liu
ResearchOpen Access24 Sept 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-13
Evidence from coupled ¹⁴⁷Sm–¹⁴³Nd and ¹⁴⁶Sm–¹⁴²Nd systematics for very early (4.5-Gyr) differentiation of the Earth's mantle

Charles L. Harper Jr
Stein B. Jacobsen
Research31 Dec 1992
Nature

Volume: 360, P: 728-732
Lead 210 and moss-increment dating of two Finnish Sphagnum hummocks

Farid El-Daoushy
Kimmo Tolonen
Rolf Rosenberg
Research01 Apr 1982
Nature

Volume: 296, P: 429-431
Swarming of Odontosyllis phosphorea, Moore, and of other Polychæta near Nanaimo, B.C.

E. BERKELEY
Research28 Dec 1935
Nature

Volume: 136, P: 1029
Enantioselective type II intramolecular [5 + 2] cycloadditions of oxidopyrylium ylides using chiral-phosphoric-acid catalysis

Intramolecular [5 + 2] cycloaddition reactions of oxidopyrylium ylides provide access to privileged bridged seven-membered polycyclic structures. Now, an enantioselective method enabled by a non-covalent activation strategy using chiral acid catalysis is reported, allowing multiple stereogenic centres to be constructed in one step with high efficiency, enantioselectivity and diastereoselectivity.

Liangliang Yang
Ka Lok Chan
Jianwei Sun
Research12 May 2025
Nature Synthesis

Volume: 4, P: 1223-1231
Single-cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

This resource highlights the compositional and transcriptional remodelling of abdominal subcutaneous adipose tissue (SAT) in humans undergoing initial lifestyle-induced weight loss followed by bariatric surgery, with implications for modulating tissue function, systemic metabolism and inflammation.

Anne Loft
Rasmus Rydbirk
Susanne Mandrup
Research12 Jan 2026
Nature Metabolism

Volume: 8, P: 260-278
Urinary Excretion of Isethionic Acid in Man

JØRGEN G. JACOBSEN
LINDA L. COLLINS
LLOYD H. SMITH JUN.
Research17 Jun 1967
Nature

Volume: 214, P: 1247-1248
Enantioselective organocatalytic cycloadditions for the synthesis of medium-sized rings

Enantioselective synthesis of medium-sized rings by organocatalytic cycloadditions offers opportunities that are complementary to metal-catalysed cycloadditions. This Review discusses the ability of organocatalytic cycloadditions to synthesize stereodefined medium-sized ring architectures, critically evaluates current synthetic strategies, and highlights avenues for further development.

Jan Otevrel
Macarena Eugui
Karl Anker Jørgensen
Reviews13 Nov 2023
Nature Synthesis

Volume: 2, P: 1142-1158
Palaeolimnology and archaeology of Holocene deposits north-east of Lake Turkana, Kenya

R. B. Owen
J. W. Barthelme
A. Vincens
Research05 Aug 1982
Nature

Volume: 298, P: 523-529
Subsurface movements of stone artefacts and their implications for the prehistory of Central Africa

D. Cahen
J. Moeyersons
Research28 Apr 1977
Nature

Volume: 266, P: 812-815
Pseudofertilization in the Genus Lumbricillus (Enchytraeidae)

B. CHRISTENSEN
F. B. O'CONNOR
Research12 Apr 1958
Nature

Volume: 181, P: 1085-1086
A mechanism for magmatic accretion under spreading centres

John A. Whitehead Jr
Henry J. B. Dick
Hans Schouten
Research08 Nov 1984
Nature

Volume: 312, P: 146-148
Effect of X-Rays on the Morphogenesis of the Embryonic Chick Tibiotarsus

J. D. BIGGERS
R. B. L. GWATKIN
Research11 Apr 1964
Nature

Volume: 202, P: 152-154
Intensity Fluctuation Spectroscopy of Motile Microorganisms

DALE W. SCHAEFER
GORDON BANKS
SEYMOUR S. ALPERT
Research08 Mar 1974
Nature

Volume: 248, P: 162-164
Protein Regge Trajectories, Phase Coexistence and Loop Aetiology in Alzheimers Disease

Antti Niemi
Andrey Krokhotin
ResearchOpen Access13 Jun 2011
Nature Precedings

P: 1
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

The commitment stage at which progenitors seed the thymus remains unclear. Jacobsen and colleagues show that the earliest progenitors in the neonatal thymus have combined myeloid, T lymphocyte and B lymphocyte potential but not megakaryocyte-erythroid potential.

Sidinh Luc
Tiago C Luis
Sten Eirik W Jacobsen
Research19 Feb 2012
Nature Immunology

Volume: 13, P: 412-419
Tandem synthesis of alternating polyesters from renewable resources

Biomass-derived monomers are a renewable resource for the production of polymers. Robertet al. develop an auto-tandem catalytic transformation for the synthesis of aliphatic polyesters—'activated' monomers are prepared from dicarboxylic acids, which can be copolymerized with epoxides.

Carine Robert
Frédéric de Montigny
Christophe M. Thomas
ResearchOpen Access13 Dec 2011
Nature Communications

Volume: 2, P: 1-6
Clinical significance of DNA ploidy and S-phase fraction and their relation to p53 protein, c-erbB-2 protein and HCG in operable muscle-invasive bladder cancer

SD Fosså
AA Berner
EO Pettersen
Research01 Sept 1993
British Journal of Cancer

Volume: 68, P: 572-578
Salting-out in Amphiphilic Gels as a New Approach to Hydrophobia Adsorption

JERKER PORATH
LARS SUNDBERG
INGMAR OLSSON
Research26 Oct 1973
Nature

Volume: 245, P: 465-466
Substrates of Kinin-releasing Enzymes isolated from Horse Plasma

OLGA B. HENRIQUES
NATALIA KAURITCHEVA
MIRA ASTRAKAN
Research09 Sept 1967
Nature

Volume: 215, P: 1200-1201
Water Exchange between Insects and Air Moisture

J. GOVAERTS
J. LECLERCQ
Research13 Apr 1946
Nature

Volume: 157, P: 483
Enantiodivergent epoxidation of alkenes with a photoswitchable phosphate manganese-salen complex

Developing enantiodivergent catalysts capable of preparing both enantiomeric products from one substrate in a controlled fashion is challenging. Now, a manganese(III)-salen complex with a chiral photoswitchable phosphate counterion is reported for the epoxidation of alkenes in a stereoselective manner, where irradiation with light allows access to either enantiomer of the epoxide.

Xiaofei Chen
Pieter J. Gilissen
Roeland J. M. Nolte
Research22 Sept 2022
Nature Synthesis

Volume: 1, P: 873-882
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Olweus and colleagues identify a T cell receptor reactive against the recurrent D835Y driver mutation in FLT3 in acute myeloid leukemia and show that engineered T cells against this neoantigen provide efficient immunotherapy.

Eirini Giannakopoulou
Madeleine Lehander
Johanna Olweus
ResearchOpen Access02 Oct 2023
Nature Cancer

Volume: 4, P: 1474-1490
Taxonomic and functional signatures of smoking and periodontitis severity in the subgingival microbiome of older adults

Jale Moradi
Ellen Berggreen
Randi Jacobsen Bertelsen
ResearchOpen Access29 Dec 2025
npj Aging

Volume: 12, P: 1-10
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

Akhteruzzaman Molla
Marina Korneyeva
Dale J. Kempf
Research01 Jul 1996
Nature Medicine

Volume: 2, P: 760-766
The intrinsic factor–vitamin B₁₂ receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

Renata Kozyraki
John Fyfe
Søren K. Moestrup
Research01 Jun 1999
Nature Medicine

Volume: 5, P: 656-661
Closed-loop recycling of mixed polyesters via catalytic methanolysis and monomer separations

Net-zero bioplastics are possible when combined with high recycling rates. This study presents a mixed polyester recycling process integrated with monomer separation and purification for both fossil- and bio-based plastics. Techno-economic and life cycle analyses confirm its environmental and commercial advantages, advancing the path toward circular, low-emission polyester plastics.

Julia B. Curley
Yuanzhe Liang
Katrina M. Knauer
Research08 Sept 2025
Nature Chemical Engineering

Volume: 2, P: 568-580
Evidence for extreme mantle fractionation in early Archaean ultramafic rocks from northern Labrador

Kenneth D. Collerson
Lisa M. Campbell
Zenon A. Palacz
Research17 Jan 1991
Nature

Volume: 349, P: 209-214
Enantioconvergent nucleophilic substitution via synergistic phase-transfer catalysis

The catalytic enantioconvergent nucleophilic fluorination of alkyl halides using inexpensive alkali metal fluorides is a persistent challenge. Now this has been achieved by synergistic hydrogen bonding phase-transfer catalysis combining a chiral bis-urea hydrogen bond donor and an onium salt.

Claire Dooley
Francesco Ibba
Véronique Gouverneur
ResearchOpen Access13 Feb 2025
Nature Catalysis

Volume: 8, P: 107-115
Pleistocene sediments beneath the Ross Ice Shelf

Thomas B. Kellogg
Davida E. Kellogg
Research10 Sept 1981
Nature

Volume: 293, P: 130-133
A functional and structural basis for TCR cross-reactivity in multiple sclerosis

Heather L.E. Lang
Helle Jacobsen
Lars Fugger
Research03 Sept 2002
Nature Immunology

Volume: 3, P: 940-943
A Cambrian crown annelid reconciles phylogenomics and the fossil record

Dannychaeta tucolus, a bristle worm from the early Cambrian period, belongs to crown annelids, and has characters that provide evidence of ecological and morphological diversity in ancient annelids, thus reconciling the fossil record with molecular phylogenetic analyses.

Hong Chen
Luke A. Parry
Xiaoya Ma
Research11 Jun 2020
Nature

Volume: 583, P: 249-252
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

The identity and lineage potential of the embryonic thymus-seeding progenitors that first seed the embryonic thymic rudiment is unclear. Jacobsen and colleagues find that these cells do not include multipotent stem cells or T cell–restricted progenitors but instead are lympho-myeloid progenitors.

Tiago C Luis
Sidinh Luc
Sten Eirik W Jacobsen
Research03 Oct 2016
Nature Immunology

Volume: 17, P: 1424-1435
Pb, Sr and Nd isotopic evidence for sources of southern African Cretaceous kimberlites

Craig B. Smith
Research01 Jul 1983
Nature

Volume: 304, P: 51-54
Assessing pre- and post-zygotic barriers between North Atlantic eels (Anguilla anguilla and A. rostrata)

M W Jacobsen
L Smedegaard
M M Hansen
Research09 Nov 2016
Heredity

Volume: 118, P: 266-275
Glicentin inhibits gastric acid secretion in the rat

P. Kirkegaard
A. J. Moody
J. Christiansen
Research13 May 1982
Nature

Volume: 297, P: 156-157
Demonstration of Super-X divertor exhaust control for transient heat load management in compact fusion reactors

Managing power exhaust in fusion reactors is a key challenge, especially in compact designs for cost-effective commercial energy. This study shows how alternative divertor configurations improve exhaust control, enhance stability, absorb transients and enable independent plasma regulation.

B. Kool
K. Verhaegh
V. Zamkovska
ResearchOpen Access05 Sept 2025
Nature Energy

Volume: 10, P: 1116-1131
Engineered cytochrome P450 for direct arylalkene-to-ketone oxidation via highly reactive carbocation intermediates

The direct regioselective oxidation of internal alkenes to ketones poses an important synthetic challenge. Now, directed evolution of a cytochrome P450 enzyme affords a ketone synthase that can efficiently oxidize internal arylalkenes directly to ketones with high chemo- and regioselectivity.

Sebastian Gergel
Jordi Soler
Stephan C. Hammer
ResearchOpen Access13 Jul 2023
Nature Catalysis

Volume: 6, P: 606-617
Record of emergent continental crust ∼3.5 billion years ago in the Pilbara craton of Australia

Roger Buick
J. R. Thornett
M. Savage
Research15 Jun 1995
Nature

Volume: 375, P: 574-577
Diastereodivergent nucleophile–nucleophile alkene chlorofluorination

Unlike homo-dihalogenation, selective hetero-dihalogenation reactions are underdeveloped. Now an oxidative alkene hetero-dihalogenation reaction adds chloride and fluoride ions over unactivated alkenes with high regio-, chemo- and diastereoselectivity. A switch in the mechanism triggers a reversal of the diastereoselectivity to promote either anti- or syn-addition.

Sayad Doobary
Andrew J. D. Lacey
Alastair J. J. Lennox
ResearchOpen Access01 Jul 2024
Nature Chemistry

Volume: 16, P: 1647-1655
Candida albicans colonization in the human colon correlates with a reduction in acetate- and butyrate-producing bacteria, as simulated using the M-SHIME® model

Benoît Marsaux
Warre d’Hoker
Tom Van de Wiele
ResearchOpen Access26 Aug 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-15
Sr and Nd isotope geochemistry of oceanic basalts and mantle evolution

W. M. White
A. W. Hofmann
Research01 Apr 1982
Nature

Volume: 296, P: 821-825
Neodymium and lead isotope evidence for enriched early Archaean crust in North America

Samuel A. Bowring
Janet E. King
Frank A. Podosek
Research20 Jul 1989
Nature

Volume: 340, P: 222-225
Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression

Sherman and colleagues show that ATX suppresses the accumulation of eosinophils in the tumor microenvironment of pancreatic cancer via suppression of CCL11 expression and find that ATX inhibition increases eosinophil influx, promoting tumor cell death.

Sohinee Bhattacharyya
Chet Oon
Mara H. Sherman
ResearchOpen Access09 Jan 2024
Nature Cancer

Volume: 5, P: 283-298

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