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Showing 1–4 of 4 results
Advanced filters: Author: Baoquan Zhan Clear advanced filters
  • Despite the growing demand for optically active boron dipyrromethenes (BODIPYs), which are useful in live cell imaging, photodynamic therapy, and fluorescent materials science, the synthesis of chiral 3-amino-BODIPYs remains a challenge. Herein, the authors report the first synthesis of boron-stereogenic 3-amino-BODIPYs via a palladium-catalyzed desymmetric C–N cross-couplings.

    • Baoquan Zhan
    • Li-Qing Ren
    • Chuan He
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8
  • Even though chiroptical luminophores have high potential for optoelectronic innovation and precision bioimaging, their rational engineering remains constrained by synthetic limitations. Here, the authors report a streamlined and programmable asymmetric synthesis platform enabling systematic construction of boron-stereogenic boron dipyrromethenes (BODIPYs) with near-infrared chiroptical activity.

    • Jiayi Zhao
    • Li-Qing Ren
    • Chuan He
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10
  • Boron dipyrromethenes (BODIPYs) have found widespread applications owing to their spectroscopic and photophysical properties, but strategies for the synthesis of enantioenriched boron-stereogenic BODIPYs are lacking. Now a modular enantioselective assembly of multi-substituted boron-stereogenic BODIPYs via a Pd-catalysed desymmetric Suzuki coupling has been developed, giving access to a range of highly functionalized chiral BODIPYs.

    • Li-Qing Ren
    • Baoquan Zhan
    • Chuan He
    Research
    Nature Chemistry
    Volume: 17, P: 83-91