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Showing 1–2 of 2 results
Advanced filters: Author: Beatriz F. Carniel Clear advanced filters

  • Using a Streptococcus pneumoniae human challenge model, the authors here show that baseline nasal microbiota profiles are associated with pneumococcal acquisition and density, independent of live-attenuated influenza vaccine (LAIV) administration, and with mucosal cytokine responses to LAIV.

    • Wouter A. A. de Steenhuijsen Piters
    • Simon P. Jochems
    • Debby Bogaert
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-9

  • Pneumococcal carriage in the upper respiratory tract is an important determinant of influenza severity. Jochems et al. use human systems analysis to show that influenza-induced inflammation increases bacterial burden in the nasal cavity with implications for secondary bacterial pneumonia.

    • Simon P. Jochems
    • Fernando Marcon
    • Daniela M. Ferreira
    Research
    Nature Immunology
    Volume: 19, P: 1299-1308