Schistosomiasis, a neglected tropical disease, is caused by flatworms such as Schistosoma mansoni. Here, Hagen et al. describe a lentivirus-based transduction system to deliver microRNA-adapted small hairpin RNAs into S. mansonito inhibit transcription of selected genes implicated in the disease process.
- Jana Hagen
- Neil D. Young
- Bernd H. Kalinna
