Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–12 of 12 results
Advanced filters: Author: Bessie Young Clear advanced filters

  • Social and environmental exposures are strong drivers of health inequity and adverse health outcomes. However, data from studies that examine the longitudinal effect of social and environmental exposure burdens on kidney disease outcomes are limited. The environmental justice index–social environmental ranking, although imperfect, provides an important tool to address this gap in knowledge.

    • Mukoso N. Ozieh
    • Bessie A. Young
    News & Views
    Nature Reviews Nephrology
    Volume: 21, P: 437-438

  • Kidney disease disproportionately affects American Indian and Alaska Native (AI/AN) communities, largely owing to adverse social drivers of health that stem from systemic issues including colonization, structural racism and historical trauma. Kidney health equity for AI/AN communities requires systemic and multilevel interventions across the CKD spectrum and life course.

    • Reya H. Mokiao
    • Jason F. Deen
    • Bessie A. Young
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 21, P: 360-361

  • Comprehensive integration of gene expression with epigenetic features is needed to understand the transition of kidney cells from health to injury. Here, the authors integrate dual single nucleus RNA expression and chromatin accessibility, DNA methylation, and histone modifications to decipher the chromatin landscape of the kidney in reference and adaptive injury cell states, identifying a transcription factor network of ELF3, KLF6, and KLF10 which regulates adaptive repair and maladaptive failed repair.

    • Debora L. Gisch
    • Michelle Brennan
    • Michael T. Eadon
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21

  • Concerns regarding the incorrect use of race as a biological construct and the resulting negative effect on health equity have led to reconsideration of the inclusion of race in equations for estimating glomerular filtration rate. Now, two studies report that cystatin-C-based equations can accurately estimate glomerular filtration rate independent of race.

    • Bessie A. Young
    News & Views
    Nature Reviews Nephrology
    Volume: 18, P: 201-202

  • Racial and ethnic minoritized populations are underrepresented in clinical trials in nephrology, but overrepresented in adverse kidney disease outcomes. Targeted enrolment, revision of problematic policies, inclusion of minoritized populations in trial planning, and language-, race- and ethnicity-concordant investigative teams can improve representation in clinical trials.

    • Bessie A. Young
    • Sylvia E. Rosas
    News & Views
    Nature Reviews Nephrology
    Volume: 19, P: 627-628

  • Upon its 'reinvention', thalidomide was quickly applied to 'microenvironment-dependent' diseases such as multiple myeloma, yet its role in the solid tumor spectrum has not been validated. A report into recurrent prostate cancer by Figg et al.1 shows that thalidomide can reduce time to PSA progression in patients treated with androgen deprivation therapy.

    • Eleni Efstathiou
    • Christopher J. Logothetis
    News & Views
    Nature Reviews Urology
    Volume: 6, P: 248-250