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Showing 1–2 of 2 results
Advanced filters: Author: Bilel Bdiri Clear advanced filters

  • PPARγ regulates glucose and lipid metabolism, yet safer PPARγ-targeted insulin sensitizers are needed to treat metabolic disorders. Here, Kuang-Ting et al. elucidate structure–function relationships of non-covalent inverse agonists that enhance receptor binding and improve insulin sensitivity, providing a framework for next-generation drug design.

    • Kuang-Ting Kuo
    • Bilel Bdiri
    • Patrick R. Griffin
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-17

  • In biological systems, controlled molecular motion along a particular path is realized by protein motors that travel along microtubule filaments. Now, control of motion with light has been achieved in a synthetic supramolecular system, in which anionic porphyrin molecules move along the fibres of a bis-imidazolium gel upon irradiation.

    • Mario Samperi
    • Bilel Bdiri
    • David B. Amabilino
    Research
    Nature Chemistry
    Volume: 13, P: 1200-1206