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Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila

Drosophila Microproteins Simba1/2 act in neural stem cells and blood-brain-barrier glia to promote reactivation of neural stem cells via activating WNT/Wingless signaling, while human ortholog ZNF706 is found to have a conserved role in activating WNT pathway.

Jiaen Lin
Qiannan Deng
Hongyan Wang
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-17
A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines

This analysis provides a collection of sequencing datasets generated from long-read and short-read RNA sequencing, serving as a valuable resource for transcriptome profiling.

Ying Chen
Nadia M. Davidson
Jonathan Göke
ResearchOpen Access13 Mar 2025
Nature Methods

Volume: 22, P: 801-812
TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex

Wen Hsin Lee
Lee Yee Choong
Yoon Pin Lim
ResearchOpen Access13 Jun 2016
Scientific Reports

Volume: 6, P: 1-16