Stress-induced behavioural measures of anhedonia in adult mice, but not measures of behavioural despair, required a decrease in the strength of excitatory synapses on D1 dopamine receptor-expressing nucleus accumbens medium spiny neurons owing to activation of melanocortin 4 receptors.
- Byung Kook Lim
- Kee Wui Huang
- Robert C. Malenka