Nature Search

Impact of household size and co-resident multimorbidity on unplanned hospitalisation and transition to care home

The ability to manage ill health and care needs might be affected by who a person lives with. Here, authors show that living alone or with co-residents with multimorbidity poses additional risk for unplanned hospitalisation and care home transition beyond an individual’s characteristics.

Clare MacRae
Stewart W. Mercer
Bruce Guthrie
ResearchOpen Access17 Feb 2025
Nature Communications

Volume: 16, P: 1-8
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Shilpa Nadimpalli Kobren
Mikhail A. Moldovan
Shamil R. Sunyaev
ResearchOpen Access07 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases

Genome-wide analyses of blood cell phenotypes derived from perturbations coupled with flow cytometry-based functional readouts identify loci associated with latent cellular traits, yielding insights into biological mechanisms underlying common diseases.

Max Homilius
Wandi Zhu
Rahul C. Deo
ResearchOpen Access04 Dec 2023
Nature Genetics

Volume: 56, P: 37-50
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

Brenda Gerull
Arnd Heuser
Ludwig Thierfelder
Research17 Oct 2004
Nature Genetics

Volume: 36, P: 1162-1164
Common variants in KCNN3 are associated with lone atrial fibrillation

Patrick Ellinor and colleagues report a genome-wide association study identifying variants in KCNN3 associated to lone atrial fibrillation.

Patrick T Ellinor
Kathryn L Lunetta
Stefan Kääb
Research21 Feb 2010
Nature Genetics

Volume: 42, P: 240-244
Robustly measuring multimorbidity using disparate linked datasets

Prigge et al. examine how the choice of data source affects the prevalence of 80 individual long-term conditions and multimorbidity by testing data from the UK Biobank, linked primary care records, hospital/cancer registry records, and all three data sources together. Their results highlight the large impact of the choice of data source used.

Regina Prigge
Kelly J. Fleetwood
Bruce Guthrie
ResearchOpen Access08 Jul 2025
Communications Medicine

Volume: 5, P: 1-9
Author Correction: Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Amendments and Corrections17 Dec 2020
Nature Biotechnology

Volume: 39, P: 115
Urogenital tuberculosis — epidemiology, pathogenesis and clinical features

Urogenital tuberculosis can be easily overlooked owing to non-specific symptoms, varying manifestations and a lack of awareness of the disease. In this Review, Muneer and colleagues provide a comprehensive overview of the epidemiology, pathogenesis, clinical features, diagnosis and management of this disease.

Asif Muneer
Bruce Macrae
Alimuddin Zumla
Reviews23 Sept 2019
Nature Reviews Urology

Volume: 16, P: 573-598
Supporting US public health experts

Ron Cohen
Cedric Francois
Sandy Zweifach
Correspondence25 Nov 2020
Nature Biotechnology

Volume: 38, P: 1381-1384
Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer

J Bruce
A J Thornton
A M Thompson
ResearchOpen Access31 Jul 2012
British Journal of Cancer

Volume: 107, P: 937-946
An association between the PTGS2 rs5275 polymorphism and colorectal cancer risk in families with inherited non-syndromic predisposition

Jason Ross
Linda Lockett
Garry N Hannan
Research27 Mar 2013
European Journal of Human Genetics

Volume: 21, P: 1389-1395

Search

Impact of household size and co-resident multimorbidity on unplanned hospitalisation and transition to care home

Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases

Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

Common variants in KCNN3 are associated with lone atrial fibrillation

Robustly measuring multimorbidity using disparate linked datasets

Author Correction: Supporting US public health experts

Urogenital tuberculosis — epidemiology, pathogenesis and clinical features

Supporting US public health experts

Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer

An association between the PTGS2 rs5275 polymorphism and colorectal cancer risk in families with inherited non-syndromic predisposition

Search

Quick links

Search

Filter By:

Search

Quick links